Difference between revisions of "MmgA"
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Revision as of 13:52, 16 May 2013
- Description: degradative acetoacetyl-CoA thiolase
| Gene name | mmgA |
| Synonyms | yqiL |
| Essential | no |
| Product | degradative acetoacetyl-CoA thiolase |
| Function | mother cell metabolism, leucine utilization |
| Gene expression levels in SubtiExpress: mmgA | |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 41 kDa, 5.904 |
| Gene length, protein length | 1179 bp, 393 aa |
| Immediate neighbours | mmgB, yqiK |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
sporulation proteins, utilization of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24170
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2 acetyl-CoA = CoA + acetoacetyl-CoA PubMed
- Protein family: thiolase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3SS6 (the protein of B. anthracis, 44% identity, 73% similarity)
- UniProt: P45855
- KEGG entry: [3]
- E.C. number: 2.3.1.9
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659]
[WorldCat.org]
[DOI]
(I p)
Jason J Reddick, Jayme K Williams
The mmgA gene from Bacillus subtilis encodes a degradative acetoacetyl-CoA thiolase.
Biotechnol Lett: 2008, 30(6);1045-50
[PubMed:18246303]
[WorldCat.org]
[DOI]
(P p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
E M Bryan, B W Beall, C P Moran
A sigma E dependent operon subject to catabolite repression during sporulation in Bacillus subtilis.
J Bacteriol: 1996, 178(16);4778-86
[PubMed:8759838]
[WorldCat.org]
[DOI]
(P p)
