Protein secretion

Parent categories	3. Information processing 3.3. Protein synthesis, modification and degradation
Neighbouring categories	3.3.1. Translation 3.3.2. Chaperones/ protein folding 3.3.3. Protein modification 3.3.4. Protein secretion 3.3.5. Proteolysis
Related categories	signal recognition particle
Overview on the categories (Excel file) All genes and their categories (Excel file)

Genes in this functional category

• comC
• csaA
• ecsA
• ecsB
• ffh
• ftsY
• lspA
• mstX
• prsA
• rnc
• scr
• secA
• secDF
• secE
• secG
• secY
• sipS
• sipT
• sipU
• sipV
• sipW
• spoIIIAB
• spoIIIAC
• spoIIIAD
• spoIIIAE
• spoIIIAF
• spoIIIAG
• spoIIIAH
• spoIIIJ
• sppA
• tatAC
• tatAD
• tatAY
• tatCD
• tatCY
• tepA
• yhcS
• yidC2

Additional candidates (based on similarity)

• yacD
• yobE
• yoqW

Important reviews

• The structure of a Tat-dependent signal peptide (PhoD) can be found here: PubMed

Tracy Palmer, Ben C Berks
The twin-arginine translocation (Tat) protein export pathway.
Nat Rev Microbiol: 2012, 10(7);483-96
[PubMed:22683878] [WorldCat.org] [DOI] (I e)

Brian M Forster, Hélène Marquis
Protein transport across the cell wall of monoderm Gram-positive bacteria.
Mol Microbiol: 2012, 84(3);405-13
[PubMed:22471582] [WorldCat.org] [DOI] (I p)

Olaf Schneewind, Dominique M Missiakas
Protein secretion and surface display in Gram-positive bacteria.
Philos Trans R Soc Lond B Biol Sci: 2012, 367(1592);1123-39
[PubMed:22411983] [WorldCat.org] [DOI] (I p)

Gustavo A de Souza, Nils A Leversen, Hiwa Målen, Harald G Wiker
Bacterial proteins with cleaved or uncleaved signal peptides of the general secretory pathway.
J Proteomics: 2011, 75(2);502-10
[PubMed:21920479] [WorldCat.org] [DOI] (I p)

Colin R Harwood, Rocky Cranenburgh
Bacillus protein secretion: an unfolding story.
Trends Microbiol: 2008, 16(2);73-9
[PubMed:18182292] [WorldCat.org] [DOI] (P p)

Arnold J M Driessen, Nico Nouwen
Protein translocation across the bacterial cytoplasmic membrane.
Annu Rev Biochem: 2008, 77;643-67
[PubMed:18078384] [WorldCat.org] [DOI] (P p)

Girbe Buist, Anja N J A Ridder, Jan Kok, Oscar P Kuipers
Different subcellular locations of secretome components of Gram-positive bacteria.
Microbiology (Reading): 2006, 152(Pt 10);2867-2874
[PubMed:17005968] [WorldCat.org] [DOI] (P p)

Kunio Yamane, Keigo Bunai, Hiroshi Kakeshita
Protein traffic for secretion and related machinery of Bacillus subtilis.
Biosci Biotechnol Biochem: 2004, 68(10);2007-23
[PubMed:15502345] [WorldCat.org] [DOI] (P p)

Harold Tjalsma, Haike Antelmann, Jan D H Jongbloed, Peter G Braun, Elise Darmon, Ronald Dorenbos, Jean-Yves F Dubois, Helga Westers, Geeske Zanen, Wim J Quax, Oscar P Kuipers, Sierd Bron, Michael Hecker, Jan Maarten van Dijl
Proteomics of protein secretion by Bacillus subtilis: separating the "secrets" of the secretome.
Microbiol Mol Biol Rev: 2004, 68(2);207-33
[PubMed:15187182] [WorldCat.org] [DOI] (P p)

J de Keyzer, C van der Does, A J M Driessen
The bacterial translocase: a dynamic protein channel complex.
Cell Mol Life Sci: 2003, 60(10);2034-52
[PubMed:14618254] [WorldCat.org] [DOI] (P p)