Difference between revisions of "SpoIIR"

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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigE]] activation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigE]] activation
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU36970 spoIIR]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36970 spoIIR]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIIR SpoIIR]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIIR SpoIIR]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywlB]]'', ''[[ywlA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ywlB]]'', ''[[ywlA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15714&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36970 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36970 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36970 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIR_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIR_context.gif]]

Revision as of 14:05, 13 May 2013

  • Description: required for processing and compartmentalization of pro-SigE

Gene name spoIIR
Synonyms ipc-27d, csfX
Essential no
Product morphological chekcpoint for SigE processing
Function control of SigE activation
Gene expression levels in SubtiExpress: spoIIR
Interactions involving this protein in SubtInteract: SpoIIR
MW, pI 25 kDa, 4.737
Gene length, protein length 672 bp, 224 aa
Immediate neighbours ywlB, ywlA
Sequences Protein DNA Advanced_DNA
Genetic context
SpoIIR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpoIIR expression.png
























Categories containing this gene/protein

sigma factors and their control, sporulation proteins

This gene is a member of the following regulons

SigF regulon

The gene

Basic information

  • Locus tag: BSU36970

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: interacts with and activates the pro-SigE protease SpoIIGA in the intermembrane space between the forespore and the mother cell PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • likely acylated on Thr-27 PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • localizes initially to the forespore septal membrane (in a SpoIIGA-dependent manner), is then exported to the intermembrane space between the forespore and the mother cell PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: spoIIR (according to DBTBS)
  • Regulation:
    • expressed early during sporulation in the forespore (SigF) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed