Difference between revisions of "HrcA"
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|colspan="2" | '''Genetic context''' <br/> [[Image:hrcA_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:hrcA_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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+ | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hrcA_2628606_2629637_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:hrcA_expression.png|500px]] | ||
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Revision as of 08:48, 20 April 2012
- Description: transcriptional repressor of class I heat-shock genes
Gene name | hrcA |
Synonyms | yqxE, yqeS |
Essential | no |
Product | transcriptional repressor |
Function | regulation of chaperone gene expression |
Interactions involving this protein in SubtInteract: HrcA | |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 38 kDa, 6.079 |
Gene length, protein length | 1029 bp, 343 aa |
Immediate neighbours | grpE, hemN |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
transcription factors and their control, heat shock proteins
This gene is a member of the following regulons
The HrcA regulon:
The gene
Basic information
- Locus tag: BSU25490
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription repressor of the * hrcA-grpE-dnaK-dnaJ-yqeT-yqeU-yqeV and groES-groEL operons (at low/ normal temperatures)
- Protein family: hrcA family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): GroEL acts as co-repressor
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P25499
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Wolfgang Schumann, Bayreuth University, Germany Homepage
Thomas Wiegert, University of Bayreuth, Germany Homepage
Your additional remarks
References