Difference between revisions of "YodU"
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | + | {{SubtiWiki regulon|[[SigK regulon]]}}, | |
| + | {{SubtiWiki regulon|[[GerE regulon]]}} | ||
=The gene= | =The gene= | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ypqP_2151626_2152045_1 yodU] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ypqP_2151626_2152045_1 yodU] {{PubMed|22383849}} | ||
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|25299644,15383836}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed late during [[sporulation]] in the mother cell ([[SigK]], [[GerE]]) {{PubMed|25299644,15383836}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[GerE]]: transcription activation {{PubMed|25299644,15383836}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed> 25299644 </pubmed> | + | <pubmed> 25299644 15383836 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:37, 10 October 2014
- Description: , N-terminal part of the split gene spsM (together with ypqP), spore envelope polysaccharide biosynthesis, in B. subtilis 168 the gene is disrupted by the SP-beta prophage
| Gene name | yodU |
| Synonyms | ypqP |
| Essential | no |
| Product | unknown |
| Function | spore envelope polysaccharide biosynthesis |
| Gene expression levels in SubtiExpress: yodU | |
| MW, pI | 15 kDa, 9.819 |
| Gene length, protein length | 423 bp, 141 aa (SpsM: 341 aa) |
| Immediate neighbours | phy, yotN |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU19810
Phenotypes of a mutant
Database entries
- BsubCyc: BSU19810
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
- rearrangement (deletion of the SP-beta prophage and generation of the spsM gene) occurs during sporulation and in response to DNA damage to allow production of spore polysaccharide PubMed
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): EpsC (for SpsM)
Extended information on the protein
- Kinetic information:
- Domains: SpsM: Polysacc_synt_2 domain (Pfam accession number, PF02719) in the 18–296-aa region PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- secreted (according to Swiss-Prot)
Database entries
- BsubCyc: BSU19810
- Structure:
- UniProt: O34490
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- expressed late during sporulation in the mother cell (SigK, GerE) PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kimihiro Abe, Yuta Kawano, Keito Iwamoto, Kenji Arai, Yuki Maruyama, Patrick Eichenberger, Tsutomu Sato
Developmentally-regulated excision of the SPβ prophage reconstitutes a gene required for spore envelope maturation in Bacillus subtilis.
PLoS Genet: 2014, 10(10);e1004636
[PubMed:25299644]
[WorldCat.org]
[DOI]
(I e)
Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836]
[WorldCat.org]
[DOI]
(I p)
