phy
168
phytase
locus
BSU_19800
Molecular weight
41.79 kDa
pI
4.94
function
utilization of inositol hexakisphosphate (phytate)
product
3-phytase
essential
no
ec
3.1.3.8
synonyms
phy, yodV, yzxA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG4247 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,150,108 → 2,151,256
The protein
Catalyzed reaction/ biological activity
1D-myo-inositol hexakisphosphate + H2O --> 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate (according to UniProt)
[wiki|Domains]
BPP domain (aa 27-361) (according to UniProt)
Structure
[PDB|3AMR]
[AF|P42094]
[wiki|Localization]
extracellular (signal peptide) [Pubmed|18957862]
Expression and Regulation
Operons
genes
[gene|B1F5776C9882CDA4D97F2A2FBB01FAB34D21022B|phy]
description
[Pubmed|7592393]
regulatory mechanism
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|abrB]: repression, [Pubmed|20817675], in [regulon|protein:E5110D9C36E8C55AFD1419987B14A53232165F20|abrB regulon]
additional information
the gene is not expressed in 'B. subtilis' due to the absene of a functional promoter [PubMed|16980498]
Biological materials
Mutant
MGNA-B509 (yodV::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1508 NBRP B. subtilis, Japan]
BKE19800 (Δ[gene|B1F5776C9882CDA4D97F2A2FBB01FAB34D21022B|phy]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE19800 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGGTACCCTCCTCTTT, downstream forward: _UP4_TAGAATAGAAAGCAGCTTGT
BKK19800 (Δ[gene|B1F5776C9882CDA4D97F2A2FBB01FAB34D21022B|phy]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK19800 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTGGTACCCTCCTCTTT, downstream forward: _UP4_TAGAATAGAAAGCAGCTTGT
References
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Time of last update: 2025-05-16 19:16:27
Author of last update: Jstuelk