Difference between revisions of "LpdV"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[utilization of amino acids]]}} | {{SubtiWiki category|[[utilization of amino acids]]}} | ||
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* '''Protein family:''' class-I pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot) | * '''Protein family:''' class-I pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot) | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[AcoL]], [[PdhD]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lpdV_2500104_2501528_-1 lpdV] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lpdV_2500104_2501528_-1 lpdV] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigL]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed] | + | * '''[[Sigma factor]]:''' [[SigL]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed] |
* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 19:24, 8 June 2013
- Description: 2-oxoisovalerate dehydrogenase (E3 subunit, dihydrolipoamide dehydrogenase)
| Gene name | lpdV |
| Synonyms | yqiV, bkd |
| Essential | no |
| Product | 2-oxoisovalerate dehydrogenase (E3 subunit, dihydrolipoamide dehydrogenase) |
| Function | utilization of branched-chain keto acids |
| Gene expression levels in SubtiExpress: lpdV | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis, Ile, Leu, Val | |
| MW, pI | 48 kDa, 4.893 |
| Gene length, protein length | 1371 bp, 457 aa |
| Immediate neighbours | bkdAA, buk |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
BkdR regulon, CodY regulon, SigL regulon
The gene
Basic information
- Locus tag: BSU24060
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein N(6)-(dihydrolipoyl)lysine + NAD+ = protein N(6)-(lipoyl)lysine + NADH (according to Swiss-Prot)
- Protein family: class-I pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2YQU (from Thermus thermophilus (hb8 mutant), 42% identity, 55% similarity)
- UniProt: P54533
- KEGG entry: [3]
- E.C. number: 1.8.1.4
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
