Difference between revisions of "BkdB"
| Line 37: | Line 37: | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
| − | + | <br/><br/> | |
| − | |||
| − | |||
| − | |||
| − | |||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
| Line 78: | Line 74: | ||
* '''Protein family:''' 2-oxoacid dehydrogenase family (according to Swiss-Prot) | * '''Protein family:''' 2-oxoacid dehydrogenase family (according to Swiss-Prot) | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[AcoC]], [[OdhB]], [[PdhC]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
| Line 113: | Line 109: | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bkdB_2496796_2498070_-1 bkdB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bkdB_2496796_2498070_-1 bkdB] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigL]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed] | + | * '''[[Sigma factor]]:''' [[SigL]] [http://www.ncbi.nlm.nih.gov/sites/entrez/10094682 PubMed] |
* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 19:18, 8 June 2013
- Description: 2-oxoisovalerate dehydrogenase (E2 subunit, lipoamide acyltransferase)
| Gene name | bkdB |
| Synonyms | bfmBB, bfmB2, bkd |
| Essential | no |
| Product | 2-oxoisovalerate dehydrogenase (E2 subunit, lipoamide acyltransferase) |
| Function | utilization of branched-chain keto acids |
| Gene expression levels in SubtiExpress: bkdB | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis, Ile, Leu, Val | |
| MW, pI | 45 kDa, 5.301 |
| Gene length, protein length | 1272 bp, 424 aa |
| Immediate neighbours | bmrR, bkdAB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
BkdR regulon, CodY regulon, SigL regulon
The gene
Basic information
- Locus tag: BSU24030
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-methylpropanoyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-(2-methylpropanoyl)dihydrolipoyl)lysine (according to Swiss-Prot)
- Protein family: 2-oxoacid dehydrogenase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: Nucleoid (Heterogeneous) PubMed
Database entries
- Structure:
- UniProt: P37942
- KEGG entry: [3]
- E.C. number: 2.3.1.168
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
