Difference between revisions of "SpoIVCB"

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{{SubtiWiki regulon|[[SigK regulon]]}},
 
{{SubtiWiki regulon|[[SigK regulon]]}},
 
{{SubtiWiki regulon|[[SpoIIID regulon]]}}
 
{{SubtiWiki regulon|[[SpoIIID regulon]]}}
 +
 +
=The [[SigK regulon]]=
  
 
=The gene=
 
=The gene=
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* '''Paralogous protein(s):'''
 
* '''Paralogous protein(s):'''
 
=== Genes controlled by SigK ===
 
 
''[[gerE]], [[lipC]], [[surC]], [[yabG]], [[yndL]]'', ''[[yitB]]-[[yitA]]-[[yisZ]]''
 
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
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==Reviews==
 
==Reviews==
 
<pubmed>20833318 20836086 </pubmed>
 
<pubmed>20833318 20836086 </pubmed>
 
+
==The [[SigK regulon]]==
 +
<pubmed>16385044,15383836,</pubmed>
 
==Original Publications==
 
==Original Publications==
<pubmed>14526016,17720779,1900494,10438769,2492118,16385044,1691789,15383836,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 10075739 7966271 17890309 </pubmed>
+
<pubmed>14526016,17720779,1900494,10438769,2492118,1691789,2536191,2163341,10931284,1577688,9852018,1942049,7814326,8550479,11959848,9501233,10400595,2115401,7592342,1518043,8226681,9078383,2514119,10611287,14523132, 19805276 10075739 7966271 17890309 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:56, 10 December 2010



Gene name spoIVCB
Synonyms cisB, sigK
Essential no
Product RNA polymerase sporulation-specific sigma factor
(sigma-K) (N-terminal half)
Function late mother cell-specific gene expression
MW, pI 17 kDa, 8.208
Gene length, protein length 468 bp, 156 aa
Immediate neighbours nucB, spoIVCA
Gene sequence (+200bp) Protein sequence
Caution: The sequence for this gene in SubtiList contains errors
Genetic context
SpoIVCB context.gif
This image was kindly provided by SubtiList





Categories containing this gene/protein

transcription, sigma factors and their control, sporulation proteins, membrane proteins

This gene is a member of the following regulons

GerE regulon, SigE regulon, SigK regulon, SpoIIID regulon

The SigK regulon

The gene

Basic information

  • Locus tag: BSU25760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: sigma-70 factor family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:
    • SigK is activated by processing of membrane-bound pro-SigK by the SpoIVFB metalloprotease PubMed
    • spoIVCB and spoIIIC form a composite gene in the mother cell during sporulation by excising the intervening DNA sequence.

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

The SigK regulon

Jessica M Silvaggi, John B Perkins, Richard Losick
Genes for small, noncoding RNAs under sporulation control in Bacillus subtilis.
J Bacteriol: 2006, 188(2);532-41
[PubMed:16385044] [WorldCat.org] [DOI] (P p)

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

Original Publications