Difference between revisions of "GatA"
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || glutamyl-tRNA(Gln) amidotransferase | + | |style="background:#ABCDEF;" align="center"| '''Product''' || glutamyl-tRNA(Gln) amidotransferase subunit A |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || translation | |style="background:#ABCDEF;" align="center"|'''Function''' || translation | ||
| Line 74: | Line 74: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' [[GatA]]-[[GatB]]-[[GatC]] | + | * '''Interactions:''' |
| + | ** ([[GatA]]-[[GatB]]-[[GatC]])-[[GltX]]-[[trnS-Gln]] (the "transamidosome") {{PubMed|20882017}}, see a [http://www.nature.com/nature/journal/v467/n7315/fig_tab/nature09411_F3.html model of the interaction] {{PubMed|20882017}} | ||
* '''Localization:''' | * '''Localization:''' | ||
| Line 122: | Line 123: | ||
=References= | =References= | ||
| − | <pubmed>9342321,, </pubmed> | + | <pubmed>9342321, 20882017, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:44, 14 October 2010
- Description: production of glutamyl-tRNA(Gln)
| Gene name | gatA |
| Synonyms | yerM, yedB |
| Essential | yes PubMed |
| Product | glutamyl-tRNA(Gln) amidotransferase subunit A |
| Function | translation |
| Metabolic function and regulation of this protein in SubtiPathways: tRNA charging | |
| MW, pI | 52 kDa, 5.24 |
| Gene length, protein length | 1455 bp, 485 aa |
| Immediate neighbours | gatC, gatB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU06680
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate (according to Swiss-Prot)
- Protein family: amidase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O06491
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
