Difference between revisions of "ResD"

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|style="background:#ABCDEF;" align="center"| '''Product''' || [[two-component systems|two-component]] response regulator
 
|style="background:#ABCDEF;" align="center"| '''Product''' || [[two-component systems|two-component]] response regulator
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of aerobic and anaerobic respiration <br/>respiration (''[[resA]]'', ''[[ctaA]]'', ''[[qcrA]]-[[qcrB]]-[[qcrC]]'', ''[[fnr]]'', ''[[lctE]]-[[lctP]]'')
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of aerobic and anaerobic respiration <br/>respiration  
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)], [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism], [http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)], [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism], [http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
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=== Genes/ operons regulated by ResD===
 
=== Genes/ operons regulated by ResD===
  
''[[nrdI]]-[[nrdE]]-[[nrdF]]-[[ymaB]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/16885274 PubMed]
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''[[nrdI]]-[[nrdE]]-[[nrdF]]-[[ymaB]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/16885274 PubMed], ''[[resA]]'', ''[[ctaA]]'', ''[[qcrA]]-[[qcrB]]-[[qcrC]]'', ''[[fnr]]'', ''[[lctE]]-[[lctP]]''
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===

Revision as of 21:29, 27 November 2009

  • Description: two-component response regulator, regulation of aerobic and anaerobic respiration

Gene name resD
Synonyms ypxD
Essential no
Product two-component response regulator
Function regulation of aerobic and anaerobic respiration
respiration
Metabolic function and regulation of this protein in SubtiPathways:
Nucleotides (regulation), Central C-metabolism, Stress
MW, pI 27 kDa, 5.631
Gene length, protein length 720 bp, 240 aa
Immediate neighbours resE, resC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ResD context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU23120

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: OmpR family of two-component response regulators
  • Paralogous protein(s):

Genes/ operons regulated by ResD

nrdI-nrdE-nrdF-ymaB PubMed, resA, ctaA, qcrA-qcrB-qcrC, fnr, lctE-lctP

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
    • repressed when phosphate is available (PhoP) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage

Your additional remarks

References