Difference between revisions of "BacE"

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(Expression and regulation)
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* '''Operon:''' ''[[bacA]]-[[bacB]]-[[bacC]]-[[bacD]]-[[bacE]]-[[bacF]]'' {{PubMed|12372825}}  
 
* '''Operon:''' ''[[bacA]]-[[bacB]]-[[bacC]]-[[bacD]]-[[bacE]]-[[bacF]]'' {{PubMed|12372825}}  
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|19801406}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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** [[ScoC]]: transcription repression {{PubMed|19801406}}
 
** [[ScoC]]: transcription repression {{PubMed|19801406}}
  
* '''Additional information:'''  
+
* '''Additional information:'''
  
 
=Biological materials =
 
=Biological materials =

Revision as of 17:35, 8 October 2009

  • Description: efflux protein for bacilysin excretion, self-protection against bacilysin

Gene name bacE
Synonyms ywfF, ipa-84d
Essential no
Product efflux protein for bacilysin excretion
Function self-protection to bacilysin
MW, pI 43 kDa, 9.222
Gene length, protein length 1182 bp, 394 aa
Immediate neighbours bacF, bacD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwfF context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU37700

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: major facilitator superfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Takashi Inaoka, Guojun Wang, Kozo Ochi
ScoC regulates bacilysin production at the transcription level in Bacillus subtilis.
J Bacteriol: 2009, 191(23);7367-71
[PubMed:19801406] [WorldCat.org] [DOI] (I p)

Gerhard Steinborn, Mohammad-Reza Hajirezaei, Jürgen Hofemeister
bac genes for recombinant bacilysin and anticapsin production in Bacillus host strains.
Arch Microbiol: 2005, 183(2);71-9
[PubMed:15609023] [WorldCat.org] [DOI] (P p)

Ayten Yazgan Karataş, Seçil Cetin, Gülay Ozcengiz
The effects of insertional mutations in comQ, comP, srfA, spo0H, spo0A and abrB genes on bacilysin biosynthesis in Bacillus subtilis.
Biochim Biophys Acta: 2003, 1626(1-3);51-6
[PubMed:12697329] [WorldCat.org] (P p)

Takashi Inaoka, Kosaku Takahashi, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, Kozo Ochi
Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.
J Biol Chem: 2003, 278(4);2169-76
[PubMed:12372825] [WorldCat.org] [DOI] (P p)