Difference between revisions of "PTS"

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(Sugar specific PTS proteins)
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* [[PRD-containing transcription factors]]
 
* [[PRD-containing transcription factors]]
 
* [[GlpK]]
 
* [[GlpK]]
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 +
==The PTS in [[SubtiPathways|''Subti''Pathways]]==
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* [http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]
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* [http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]
  
 
==Related Lists==
 
==Related Lists==

Revision as of 20:20, 6 September 2009

The PEP:Sugar Phosphotransferase System

The PTS is a sugar transport system that couples the transport of a sugar to its phosphorylation. The phosphate group is derived from phosphoenolpyruvate (PEP) and transferred via the general PTS proteins Enzyme I (EI) and HPr to the substrate-specific Enzymes II (EII) to the incoming sugars.

In addition to its role in sugar transport, the PTS is also involved in the regulation of carbon metabolism.

General PTS proteins

Sugar specific PTS proteins

  • PtsG: glucose permease, EIICBA
  • GamP: glucosamine permease, EIICBA
  • MurP: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component
  • MtlA: mannitol permease
  • GmuA, GmuB, GmuC: galactomannan permease
  • TreP: trehalose permease
  • MalP: maltose permease
  • FruA: fructose permease
  • ManP: mannose permease
  • YpqE: unknown EIIA component
  • LevD, LevE, LevF, LevG: fructose permease
  • SacP: sucrose permease (high affinity)
  • SacY: sucrose permease (low affinity)
  • LicA, LicB, LicC: lichenan permease
  • BglP: ß-glucoside permease
  • YyzE: unknown PTS protein
  • MtlF
  • YwbA: unknown EIIC component

Proteins closely related to the PTS

  • Crh: HPr-like protein with exculsively regulatory functions (His-15 is not conserved
  • HprK: HPr-kinase, key factor for carbon catabolite repression

Non-PTS proteins controlled by PTS-dependent phosphorylation

The PTS in SubtiPathways

Related Lists

Relevant Reviews