mhqA

mhqA
168

hydroquinone-specific dioxygenase, confers resistence to methyl-hydroxyquinone

Locus
BSU_12870
Molecular weight
35.23 kDa
Isoelectric point
5.4
Protein length
316 aaSequenceBlast
Gene length
951 bpSequenceBlast
Function
resistence to methyl-hydroxyquinone
Product
hydroquinone-specific dioxygenase
Essential
no
Synonyms
mhqA, ykcA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2514 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,353,080  1,354,030
The protein
Protein family
extradiol ring-cleavage dioxygenase family (according to UniProt)
Domains
2 VOC domains (aa 5-131, aa 154-278) (according to UniProt)
Structure
3OAJ (PDB) (MhqO, 34% identical residues)
O34689 (AlphaFold)
Paralogous protein(s)
MhqE, MhqO
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
mhqA
Description
PubMed
Regulation
induced by catechol and 2-methylhydroquinone (MhqR) PubMed
Regulatory mechanism
MhqR: repression, PubMed, in mhqR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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mhqA

2025-06-01 00:28:50

ghost

52

ac5f30dccc11364ed920ad541d00a2ce9c7bfdb8

D56F44F638C5129048C0BA2AB059ACDB6F5D43B8

Biological materials
Mutant
MGNA-A737 (ykcA::erm), available at the NBRP B. subtilis, Japan
BKE12870 (mhqA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGCTGTCCCTCCAGGT,  downstream forward: _UP4_TAAATTGTGATTCTTTTGCC
BKK12870 (mhqA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATGCTGTCCCTCCAGGT,  downstream forward: _UP4_TAAATTGTGATTCTTTTGCC
References
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Page visits: 1504

Time of last update: 2025-05-31 02:25:30

Author of last update: Melvin.boenninger