dtrR

dtrR
168

D-Tyr resistance regulator (MarR family)

Locus
BSU_38450
Molecular weight
19.50 kDa
Isoelectric point
8.76
Protein length
171 aaSequenceBlast
Gene length
516 bpSequenceBlast
Function
resistance to D-Tyr
Product
transcription factor (MarR family)
Essential
no
Synonyms
dtrR, ywaE, ipa-10r
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1846 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,946,394  3,946,909
The protein
Catalyzed reaction/ biological activity
repression of the ''dtrR-tyrZ'' operon PubMed
Protein family
MarR family
Domains
HTH marR-type domain (aa 33-166) (according to UniProt)
Structure
3CDH (PDB) (from Silicibacter pomeroyi, 24% identity)
P25150 (AlphaFold)
Expression and Regulation
Operons
Genes
dtrR-tyrZ
Description
PubMed
Regulation
induced by tyrosine limitation (T-box) PubMed
Regulatory mechanism
DtrR: repression, PubMed, in dtrR regulon
T-box: RNA switch, in T-box
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dtrR→tyrZ

2025-03-17 19:38:05

ghost

74

74b2f4d2d40be21d04649012c98c32ffad1c5306

AE76E703ABACEA6477FFDE49A728A198DC210002

Biological materials
Mutant
MGNA-B219 (ywaE::erm), available at the NBRP B. subtilis, Japan
BKE38450 (dtrR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTTAGGCCTGCCTTA,  downstream forward: _UP4_GCTGACAATCTTCATACAAC
BKK38450 (dtrR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTTTTTAGGCCTGCCTTA,  downstream forward: _UP4_GCTGACAATCTTCATACAAC
References
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2D4E3D6C3634C3F42A4517D5C1A8F4F48CAFF3A6

Page visits: 2910

Time of last update: 2025-04-02 21:35:34

Author of last update: Melvin.boenninger