rhaR
168
transcriptional regulator ([wiki|DeoR family]) of the [gene|C32AE30BF7931D6171E9DE75C67504F81DD0F227|rhaEW]-[gene|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]-[gene|693040A5BA7A25AD485B7B28DBD6E8AAC77450F7|rhaB]-[gene|294C0CC675088B2A2EEFC26FAF1A628002B82C59|rhaM]-[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA] operon
locus
BSU_31210
Molecular weight
28.70 kDa
pI
7.37
function
control of rhamnose utilization
product
transcriptional regulator ([wiki|DeoR family])
essential
no
synonyms
rhaR, yulB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1349 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,201,027 → 3,201,803
The protein
[wiki|Domains]
[wiki|HTH deoR-type domain] (aa 3-58) (according to UniProt)
Structure
[AF|O05261]
Effectors of protein activity
molecular inducer: rhamnulose-1-phosphate [Pubmed|26712933]
Expression and Regulation
Operons
genes
[gene|C32AE30BF7931D6171E9DE75C67504F81DD0F227|rhaEW]-[gene|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]-[gene|693040A5BA7A25AD485B7B28DBD6E8AAC77450F7|rhaB]-[gene|294C0CC675088B2A2EEFC26FAF1A628002B82C59|rhaM]-[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA]
description
[Pubmed|26712933,22383849]
regulation
expression during spore [wiki|germination] is increased under conditions of osmotic stress [Pubmed|27766092]
regulatory mechanism
[protein|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]: repression, [Pubmed|26712933], in [regulon|protein:F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|26712933], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|26712933], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
genes
[gene|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]-[gene|693040A5BA7A25AD485B7B28DBD6E8AAC77450F7|rhaB]-[gene|294C0CC675088B2A2EEFC26FAF1A628002B82C59|rhaM]-[gene|FDDC16D57752D81299CDD426257C1CD49890C89C|rhaA]
description
[Pubmed|22383849]
regulation
expression during spore [wiki|germination] is increased under conditions of osmotic stress [Pubmed|27766092]
Biological materials
Mutant
MGNA-B546 (yulB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1545 NBRP B. subtilis, Japan]
BKE31210 (Δ[gene|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE31210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGGTAACGCCCTTCCTC, downstream forward: _UP4_CCTCTTTCGAAGAGAGGGTG
BKK31210 (Δ[gene|F574142C1E61788FF8F4B61280AD4F87292D08DF|rhaR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK31210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCGGTAACGCCCTTCCTC, downstream forward: _UP4_CCTCTTTCGAAGAGAGGGTG
References
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Time of last update: 2024-12-26 06:24:19
Author of last update: Melvin.boenninger