yfhM

yfhM
168

general stress protein, epoxide hydrolase

locus
BSU_08590
Molecular weight
32.61 kDa
pI
6.06
Protein length
Gene length
function
survival of ethanol stress
product
epoxide hydrolase
essential
no
synonyms
yfhM

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0596 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
929,725 → 930,585
The protein
Protein family
[wiki|AB hydrolase superfamily] (according to UniProt)
[wiki|Domains]
[wiki|AB hydrolase-1 domain] (aa 27-272) (according to UniProt)
Structure
[PDB|4NZZ] (from ''Bacillus Megaterium'', 33% identity)
[AF|O31581]
Additional information
subject to Clp-dependent proteolysis upon glucose starvation [PubMed|17981983]
Expression and Regulation
Operons
genes
[gene|893103B8E6163A4B403CA136A92BA3EA66DC3802|yfhK]-[gene|2B7F65B145005A8ADD2A278E3EA5A52DF162C837|yfhL]-[gene|ED478E2C37F2AD8BF06251B52511287EDB91C9EE|yfhM]
description
[Pubmed|10913081]
regulation
induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]) [Pubmed|10913081,15805528]
sigma factors
[protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB]: sigma factor, [Pubmed|10913081,15805528], in [regulon|protein:580011DE5DC40EC9E7E0512791D328FAA010DCB8|sigB regulon]
[protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW]: sigma factor, [Pubmed|9987136], in [regulon|protein:3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|sigW regulon]
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[gene|893103B8E6163A4B403CA136A92BA3EA66DC3802|yfhK]→[gene|ED478E2C37F2AD8BF06251B52511287EDB91C9EE|yfhM]

2024-10-07 16:33:21

Bzhu

90

5527a2889122b32c68f7cd90d67b08eea6544a9e

B88EAFEB7F884F08BE6A90D82989FAD011056950

Biological materials
Mutant
MGNA-C318 (yfhM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2316 NBRP B. subtilis, Japan]
BKE08590 (Δ[gene|ED478E2C37F2AD8BF06251B52511287EDB91C9EE|yfhM]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08590 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TCCGTTCGTATTGACAAACT,  downstream forward: _UP4_TAAGCTAAAATTTCTCTCCA
BKK08590 (Δ[gene|ED478E2C37F2AD8BF06251B52511287EDB91C9EE|yfhM]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08590 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_TCCGTTCGTATTGACAAACT,  downstream forward: _UP4_TAAGCTAAAATTTCTCTCCA
References
9987136,10913081,15805528,31457061

ED478E2C37F2AD8BF06251B52511287EDB91C9EE

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Time of last update: 2024-10-08 17:24:53

Author of last update: Jstuelk