yhjQ
168
copper storage protein
locus
BSU_10600
Molecular weight
11.70 kDa
pI
4.9
function
delivery of copper to [protein|73473E6556D374C8623A426E075038AD01AB7025|laccase]
product
copper storage protein
essential
no
synonyms
yhjQ, csp3
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms
This gene is a member of the following regulons
Gene
Coordinates
1,135,255 → 1,135,581
The protein
Catalyzed reaction/ biological activity
binding of Cu(I) ions (up to 80 ions per tetramer) to prevent copper toxicity [Pubmed|27991525]
Structure
[PDB|5FIG] [Pubmed|27991525]
[AF|O07571]
Expression and Regulation
Operons
genes
[gene|90E4C0FFA7678C7034657237464C2B34EE261B79|yhjR]-[gene|C3966AC2F7160228C3B155132B40F0AF71D6FECA|yhjQ]
description
[Pubmed|22383849,12480901]
regulation
expressed during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE], [protein|search|SigK], [protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]) [Pubmed|12480901,15383836]
regulatory mechanism
[protein|19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE]: repression, [Pubmed|15383836], in [regulon|protein:19228BAD44E6DA3DE908DC390FDF628C18D94E65|gerE regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|12480901], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15383836], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
Biological materials
Mutant
MGNA-B288 (yhjQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1287 NBRP B. subtilis, Japan]
BKE10600 (Δ[gene|C3966AC2F7160228C3B155132B40F0AF71D6FECA|yhjQ]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10600 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTTGATTCCCCCTGTA, downstream forward: _UP4_TAAAAAAGAGGGTTCAAAAA
BKK10600 (Δ[gene|C3966AC2F7160228C3B155132B40F0AF71D6FECA|yhjQ]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10600 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGGTTGATTCCCCCTGTA, downstream forward: _UP4_TAAAAAAGAGGGTTCAAAAA
References
Reviews
Original Publications
Page visits: 1971
Time of last update: 2024-12-21 20:12:32
Author of last update: Jstuelk