ssuA
168
aliphatic sulfonate ABC transporter (binding lipoprotein)
locus
BSU_08840
Molecular weight
36.18 kDa
pI
4.85
function
sulfonate uptake
product
aliphatic sulfonate ABC transporter (binding lipoprotein)
essential
no
synonyms
ssuA, ygbA, yzeA
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0715 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
962,179 → 963,177
The protein
Protein family
bacterial solute-binding protein ssuA/tauA family (with [protein|56E482D9CAC6E350140FD21A1C4AC8820B918CDA|ytlA], according to UniProt)
Structure
[PDB|2X26] (from E. coli,32% identity ) [pubmed|20383006]
[AF|P40400]
[wiki|Localization]
associated to the membrane (via [protein|91EAC386AD3A373E7CDE0265AA23786ADC55558A|ssuC]) [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|675CE0BCA393E9C2795032F1C0FDE6AF08B77033|ssuB]-[gene|B47C64731FCAA086CA563EEE95D3205428E51EFC|ssuA]-[gene|91EAC386AD3A373E7CDE0265AA23786ADC55558A|ssuC]-[gene|A9F7BEC330EB17CA38C4D421E8BBF58CE380559C|ssuD]-[gene|93F7A5795A423CD8DD7B070F7F37731A5E8D6321|ygaN]
description
[Pubmed|11251850]
regulation
repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16513748]
regulatory mechanism
[protein|50930C56C27D22715620A350220E3C56ADB41020|cymR]: repression, [Pubmed|16513748], in [regulon|protein:50930C56C27D22715620A350220E3C56ADB41020|cymR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|11251850], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-A252 (ygbA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/252 NBRP B. subtilis, Japan]
1A800 ( ''ssuA''::''kan''), [Pubmed|9782504], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A800&Search=1A800 BGSC]
BKE08840 (Δ[gene|B47C64731FCAA086CA563EEE95D3205428E51EFC|ssuA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE08840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCCGCTTCCGCCCTTT, downstream forward: _UP4_CAATGATGAAAGCAGAGGCT
BKK08840 (Δ[gene|B47C64731FCAA086CA563EEE95D3205428E51EFC|ssuA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK08840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCCGCTTCCGCCCTTT, downstream forward: _UP4_CAATGATGAAAGCAGAGGCT
References
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Time of last update: 2024-12-22 10:11:12
Author of last update: Jstuelk