ctaA

ctaA
168

heme A synthase

Locus
BSU_14870
Molecular weight
33.93 kDa
Isoelectric point
9.64
Protein length
Gene length
Function
heme biosynthesis
Product
heme A synthase
Essential
no
E.C.
1.3.-.-
Synonyms
ctaA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1612 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,558,034 → 1,558,954
Phenotypes of a mutant
the mutant tends to acquire suppressor mutations that result in improved growth PubMed
The protein
Catalyzed reaction/ biological activity
heme A synthesis from protoheme IX (heme B)
Protein family
COX15/ctaA family (single member, according to UniProt)
contains 8 transmembrane segments
heme B
Structure
cell membrane (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
Description
Regulation
expressed under anaerobic conditions (ResD) PubMed
Regulatory mechanism
ResD: activation, PubMed, in resD regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigE: sigma factor, PubMed, in sigE regulon
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ctaA

2024-12-21 12:48:23

ghost

66

c7717e4c7ce3c93fd497ece726ffe03b448ece94

C45F89B9D89AF4F686D0DBBFDEAD2009F145E339

Biological materials
Mutant
BKE14870 (ΔctaA::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATACAATATTCACCTTCTT,  downstream forward: _UP4_TAAGGACTCAAGACCAAAGC
BKK14870 (ΔctaA::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATACAATATTCACCTTCTT,  downstream forward: _UP4_TAAGGACTCAAGACCAAAGC
References
Reviews
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Original Publications
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B308BDECB15D68DF0EC2E49341DB5E7F9B3E14D1

Page visits: 2711

Time of last update: 2025-01-08 10:42:06

Author of last update: Christoph.elfmann