ywbH

ywbH
168

holin-like protein

Locus
BSU_38320
Molecular weight
14.12 kDa
Isoelectric point
9.59
Protein length
128 aaSequenceBlast
Gene length
387 bpSequenceBlast
Function
unknown
Product
holin-like protein
Essential
no
Synonyms
ywbH, ipa-23r, cidA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1380 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,933,209  3,933,595
Phenotypes of a mutant
a ''ywbH-ywbG'' mutant is delayed in pellicle formation PubMed
a ''ywbH-ywbG yxaK-yxaC pftA-pftB'' triple mutant is severely delayed in pellicle formation PubMed
a ''ywbH-ywbG'' overexpression strain has more robust pellicle formation PubMed
The protein
Protein family
CidA/LrgA family (with PftA, according to UniProt)
Structure
P39591 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
ywbH-ywbG
Description
PubMed
Regulation
induced by acetate (YwbI) PubMed
Regulatory mechanism
YwbI: activation, PubMed, in ywbI regulon
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ywbH→ywbG

2025-03-10 00:53:19

ghost

69

8b888b7f95218c39ab633b66f41839b48b0e4a12

C0F3774C83BBD0BC954BE909C2A1F2245DF796C1

Biological materials
Mutant
MGNA-B225 (ywbH::erm), available at the NBRP B. subtilis, Japan
BKE38320 (ywbH::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTGATGCCTCCCTTAT,  downstream forward: _UP4_AAGAGAAAGGAGAAAAAGCA
BKK38320 (ywbH::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATATTGATGCCTCCCTTAT,  downstream forward: _UP4_AAGAGAAAGGAGAAAAAGCA
References
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7DA08C189F5524D4874E2F4828264AB2671A5460

Page visits: 2769

Time of last update: 2025-04-07 08:25:10

Author of last update: Melvin.boenninger