sigO

sigO
168

[wiki|RNA polymerase] [wiki|sigma factor] SigO (with [protein|AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA])

locus
BSU_33230
Molecular weight
22.54 kDa
pI
9.78
Protein length
Gene length
function
[wiki|RNA polymerase] [wiki|sigma factor]
product
co-sigma factor with [protein|AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA]
essential
no
synonyms
sigO, yvrI

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1191 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,409,462 → 3,409,992
The protein
Protein family
[wiki|Sigma-70 factor family] (according to UniProt)
[wiki|Domains]
contains a DNA-binding helix-turn-helix motif (HTH) and the region 4.2 of Sigma factors [Pubmed|19940246]
Structure
[AF|O34843]
Expression and Regulation
Operons
genes
[gene|6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO]-[gene|AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA]
description
[Pubmed|19047353]
regulation
induced by acidic growth conditions [Pubmed|19047353]
regulatory mechanism
[protein|7098319D8E88FDC2A629A3F4A21507FD7A649385|yvrHb]: activation, [Pubmed|16306698], in [regulon|protein:7098319D8E88FDC2A629A3F4A21507FD7A649385|yvrHb regulon]
sigma factors
[protein|6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO]: sigma factor, [Pubmed|19047353], in [regulon|protein:6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO regulon]
[protein|AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA]: sigma factor, in [regulon|protein:AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA regulon]
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[gene|6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO]→[gene|AE8D4F07EFB17DA727D80229C3E72075928AA352|rsoA]

2024-08-25 16:08:58

ghost

71

aea77e80661345e9658f3f3be2c199b9bb41d9a5

7FE05DBCCA24023D39ED5555F02700870F32CAC4

Biological materials
Mutant
MGNA-B052 (yvrI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1051 NBRP B. subtilis, Japan]
BKE33230 (Δ[gene|6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE33230 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_ATGCTTCATTATCTCCTTAC,  downstream forward: _UP4_CAAAAAAAGGGGGAAAAGTA
BKK33230 (Δ[gene|6359025A73C0BD313F5BCC6F56FE88B820902AAA|sigO]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK33230 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_ATGCTTCATTATCTCCTTAC,  downstream forward: _UP4_CAAAAAAAGGGGGAAAAGTA
labs
[wiki|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
References
18573182,19047353,26651345,16306698,19940246,26367498,26400263,27558998

6359025A73C0BD313F5BCC6F56FE88B820902AAA

Page visits: 5361

Time of last update: 2024-10-10 10:29:52

Author of last update: Jstuelk