gerR

gerR
168

probably DNA-binding protein, regulates transcription of some spore coat genes

locus
BSU_15090
Molecular weight
22.22 kDa
pI
7.11
Protein length
Gene length
function
spore coat formation and resistance of spores to lysozyme
product
unknown
essential
no
ec
null
synonyms
gerR, ylbO

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5841 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,576,129  1,576,710
The protein
[wiki|Domains]
HTH myb-type domain (aa 1-61) (according to UniProt)
Structure
[AF|O34549]
Modification
phosphorylated on Ser-180 [Pubmed|20509597]
Expression and Regulation
Operons
genes
[gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]
description
[pubmed|22383849]
regulation
expressed during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE], [wiki|SpoIIID]) [Pubmed|15699190,20435725]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: activation, [Pubmed|20435725], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
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[gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]

2024-09-17 22:30:09

Jstuelk

54

4cef2b8ab37998205b5e4cc42c69e4eaf1223cac

84FC59EF0FA33C5F8E49B52978098933C9872F36

Biological materials
Mutant
MGNA-B252 (ylbO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1251 NBRP B. subtilis, Japan]
BKE15090 ([gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15090 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAATTCAATCTCCCTCCAT,  downstream forward: _UP4_TAAAGAAACGCCTGAAATGA
BKK15090 ([gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15090 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CAAATTCAATCTCCCTCCAT,  downstream forward: _UP4_TAAAGAAACGCCTGAAATGA
References
Reviews
31350897
Original Publications
15383836,15621419,20435725,12850135,12107147,20509597

0D7F5504590512E1598B94DC1734BF8FF67ED994

Page visits: 6043

Time of last update: 2024-10-09 14:30:26

Author of last update: Melvin.boenninger