gerR
168
probably DNA-binding protein, regulates transcription of some spore coat genes
locus
BSU_15090
Molecular weight
22.22 kDa
pI
7.11
function
spore coat formation and resistance of spores to lysozyme
product
unknown
essential
no
ec
null
synonyms
gerR, ylbO
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG5841 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,576,129 1,576,710
The protein
[wiki|Domains]
HTH myb-type domain (aa 1-61) (according to UniProt)
Structure
[AF|O34549]
Modification
phosphorylated on Ser-180 [Pubmed|20509597]
Expression and Regulation
Operons
genes
[gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]
description
[pubmed|22383849]
regulation
expressed during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE], [wiki|SpoIIID]) [Pubmed|15699190,20435725]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: activation, [Pubmed|20435725], in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15699190], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
MGNA-B252 (ylbO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1251 NBRP B. subtilis, Japan]
BKE15090 ([gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATTCAATCTCCCTCCAT, downstream forward: _UP4_TAAAGAAACGCCTGAAATGA
BKK15090 ([gene|0D7F5504590512E1598B94DC1734BF8FF67ED994|gerR]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15090 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATTCAATCTCCCTCCAT, downstream forward: _UP4_TAAAGAAACGCCTGAAATGA
References
Reviews
Original Publications
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Time of last update: 2024-10-09 14:30:26
Author of last update: Melvin.boenninger