rpmE
168
ribosomal protein bL31
locus
BSU_37070
Molecular weight
7.31 kDa
pI
9.16
function
translation
product
ribosomal protein L31 (bL31)
essential
no
synonyms
rpmE
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0254 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,803,081 3,803,281
Phenotypes of a mutant
delayed spore [wiki|germination] [Pubmed|25661487]
The protein
Protein family
bacterial [wiki|ribosomal protein] bL31 family (with [protein|DAE7AB27A4C42BF50556BB76F33BEFA8DF35EA3A|rpmEB], according to UniProt)
[wiki|Cofactors]
requires zinc for activity [Pubmed|19648245,15049826]
Structure
[PDB|3J9W] (the [wiki|ribosome]) [Pubmed|25903689]
[AF|Q03223]
Paralogous protein(s)
[protein|DAE7AB27A4C42BF50556BB76F33BEFA8DF35EA3A|rpmEB]
Additional information
under conditions of zinc starvation, RpmE is replaced by its paralog [protein|DAE7AB27A4C42BF50556BB76F33BEFA8DF35EA3A|rpmEB], that does not require zinc [Pubmed|15049826]
this ribosomal protein is lacking in some organisms with very small genomes [pubmed|33753464]
Expression and Regulation
Operons
genes
[gene|035154A4160F084BA1CC124D0951937B203E167D|rpmE]
description
[Pubmed|9353933]
regulation
[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
regulatory mechanism
stringent response: negative regulation, in [regulon|other_regulator:stringent response|stringent response]
[protein|035154A4160F084BA1CC124D0951937B203E167D|rpmE]: autorepression, [pubmed|32448158], in [regulon|protein:035154A4160F084BA1CC124D0951937B203E167D|rpmE regulon]
genes
[gene|9896B99346B0D3F6D57F57377DB253B46135A37A|spo0F]-[gene|800EC1F1CA8C4F2A643EDECBB684347C29CAB0CA|fbaA]-[gene|1419F2F99D924973D75EE6FAA41F9A27EC5283E1|ywjH]-[gene|523B01B5E7141C7DFC28CE67EB92580F49C20844|murAB]-[gene|0AFCE5C602B073B29DB15DB3CDD153E05E3D02BD|glpX]-[gene|7CD46C64BE69EDADF58B634DC50C3F61BFFEC5B5|rho]-[gene|035154A4160F084BA1CC124D0951937B203E167D|rpmE]
description
[pubmed|39427753]
expression
readthrough-transcription from the [protein|DC3449D5F195E5C2E9E14FEC95396C8F1FDF73B4|sigH]-dependent promoter after the initiation of sporulation in the mother cell [pubmed|39427753]
genes
[gene|7CD46C64BE69EDADF58B634DC50C3F61BFFEC5B5|rho]-[gene|035154A4160F084BA1CC124D0951937B203E167D|rpmE]
description
[pubmed|22383849]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, during vegetative growth [pubmed|39427753], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF]: sigma factor, after initiation of sporulation in the forespore [pubmed|39427753], in [regulon|protein:CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|sigF regulon]
Biological materials
Mutant
BKE37070 ([gene|035154A4160F084BA1CC124D0951937B203E167D|rpmE]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE37070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTATCCATCTCCTTCC, downstream forward: _UP4_TAATAATAGATTTCTCAACA
BKK37070 ([gene|035154A4160F084BA1CC124D0951937B203E167D|rpmE]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK37070 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTGTATCCATCTCCTTCC, downstream forward: _UP4_TAATAATAGATTTCTCAACA
References
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Time of last update: 2024-12-23 16:45:15
Author of last update: Jstuelk