Replisome
The replisome is a protein complex that is required and sufficient for replication of both leading and lagging strands.
PolC-HolA-HolB-DnaX-DnaN-DnaG-DnaC-DnaI-DnaD-SsbA-DnaE-PriA-DnaB PubMed
RecA colocalizes to the replisome in response to endogenous and exogenous DNA damage and in response to damage-independent fork arrest (formation of DNA repair centers), repair center formation depends on RecO and RecR, and is facilitated by RecF and SsbA PubMed
Related pages
Back to Protein-protein interactions
In vitro reconstitution of the replisome
<pubmed> 20122408 35635709 </pubmed>
Reviews
<pubmed>26097470 16036556 21675919,29856930 </pubmed>
Other important publications
<pubmed> 21350489 21419346</pubmed>