RNases

RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and small RNAs

Parent categories	3. Information processing 3.2. RNA synthesis and degradation
Neighbouring categories	3.2.1. Transcription 3.2.2. RNA chaperones 3.2.3. DEAD-box RNA helicases 3.2.4. RNases
Related categories	RNA degradosome
Overview on the categories (Excel file) All genes and their categories (Excel file)

Exoribonucleases

• RNase J1: 5'-3' activity

• RNase PH: 3'-5' activity
• YhaM: 3'-5' activity
• RNase R: 3'-5' activity
• polynucleotide phosphorylase: 3'-5' activity

• nano-RNase A: degrades oligonucleotides
• nano-RNase B: degrades oligonucleotides

Endoribonucleases

• RNase Y: ssRNA endonuclease
• RNase P: ssRNA endonuclease
• RNase Z: ssRNA endonuclease
• RNase Endo A
• RNase HII: cleaves RNA in RNA-DNA hybrids
• RNase HIII: cleaves RNA in RNA-DNA hybrids
• RNase Bsn: extracellular RNase
• RNase III: dsRNA endonuclease
• mini-III: dsRNA endonuclease
• RNase M5: dsRNA endonuclease

RNA pyrophosphohydrolase

• RppH

Unknown activity

• RNase J2: similar to and interacting with RNase J1, but does not seem to have an own RNase activity
• YpdQ: similar to RNase HI
• YrrK: processing of the 5' end of pre-16S rRNA
• YqfG: putative endoribonuclease, important for rRNA maturation

Labs working on RNases

• David Bechhofer
• Ciaran Condon
• Harald Putzer
• Jörg Stülke

Key original publications

<pubmed> 12884008 22537947 25099370 </pubmed>

Reviews on RNases in Bacillus subtilis

<pubmed>21334965 19767421 21976285 22550495 19215774 12794188 12490701 20659169 23403287,21957024 22568516 24064983 25292357 25878039</pubmed>