Protein families
- AAA ATPase family
- AB hydrolase superfamily
- ABC transporter superfamily
- ABCF ATPase subfamily
- ABC-2 integral membrane protein family
- ABC-4 integral membrane protein family
- Acetyltransferase family
- Acyl-CoA dehydrogenase family
- Alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family
- Aldehyde dehydrogenase family
- Aldo/keto reductase family
- Aldo/keto reductase 2 subfamily
- Alpha/beta-type SASP family
- Amino acid-polyamine-organocation (APC) superfamily
- ATP-dependent AMP-binding enzyme family
- Autoinducer-2 exporter (AI-2E) (TC 2.A.86) family
- Bacterial solute-binding protein 1 family
- Bacterial solute-binding protein 3 family
- Bacterial solute-binding protein 5 family
- Bacterial solute-binding protein 8 family
- Beta-lactamase family
- Binding-protein-dependent transport system permease family
- Carbohydrate kinase PfkB family
- Catalase family
- Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
- Cation transport ATPase (P-type) (TC 3.A.3) family
- CdaR family
- CitM transporter family (TC 2.A.11)
- Class-I aminoacyl-tRNA synthetase family
- Class-II aminoacyl-tRNA synthetase family
- Class I-like SAM-binding methyltransferase superfamily
- Class-I pyridoxal-phosphate-dependent aminotransferase family
- Class-II pyridoxal-phosphate-dependent aminotransferase family
- Class-III pyridoxal-phosphate-dependent aminotransferase family
- Class-IV pyridoxal-phosphate-dependent aminotransferase family
- Class-V pyridoxal-phosphate-dependent aminotransferase family
- Classic translation factor GTPase family
- Cof family
- CotF family
- CysTW subfamily
- Cytidine and deoxycytidylate deaminase family
- Cytochrome P450 family
- Dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family
- DinB family
- DNA polymerase type-Y family
- Drug/metabolite transporter (DMT) superfamily
- EamA transporter family
- ECF subfamily
- EmrB family
- Enoyl-CoA hydratase/isomerase family
- Extradiol ring-cleavage dioxygenase family
- FecCD subfamily
- FGGY kinase family
- Flagella basal body rod proteins family
- FtsA/MreB family
- Fur family
- 'GDSL' lipolytic enzyme family
- GerABKA family
- GerABKC lipoprotein family
- GerPA/GerPF family
- Gfo/Idh/MocA family
- Glycosyl hydrolase 1 family
- Glycosyl hydrolase 4 family
- Glycosyl hydrolase 13 family
- Glycosyl hydrolase 18 family
- Glycosyl hydrolase 43 family
- Glycosyltransferase 1 family
- Glycosyltransferase 2 family
- Glycosyltransferase 4 subfamily
- Glycosyltransferase 51 family
- HAD superfamily
- Helicase family
- Isochorismatase family
- LacI family
- LTA synthase family
- Lyase 1 family
- Major facilitator superfamily
- MalFG subfamily
- Malic enzymes family
- Mandelate racemase/muconate lactonizing enzyme family
- Membrane fusion protein (MFP) (TC 8.A.1) family
- MerR family
- Metallo-beta-lactamase superfamily
- Metallo-dependent hydrolases superfamily
- Metallophosphoesterase superfamily
- Methyltransferase superfamily
- MscS (TC 1.A.23) family
- Multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family
- MurCDEF family
- N-acetylmuramoyl-L-alanine amidase 2 family
- N-acetylmuramoyl-L-alanine amidase 3 family
- NAD(P)-dependent epimerase/dehydratase family
- Nitroreductase family
- Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily
- Nudix hydrolases
- OppBC subfamily
- 4-oxalocrotonate tautomerase family
- 2-oxoacid dehydrogenase family
- Peptidase C40 family
- Peptidase C56 family
- Peptidase M16 family
- Peptidase M20 family
- Peptidase M20A family
- Peptidase M50B family
- Peptidase S8 family
- Peptidase S11 family
- Peptidase S26 family
- Peptidase S54 family
- PEP-utilizing enzyme family
- Peroxiredoxin family
- Phage integrase family
- Phr family
- Polysaccharide deacetylase family
- Polysaccharide synthase family
- PRD-containing transcription factors
- Prokaryotic molybdopterin-containing oxidoreductase family
- Protein kinase superfamily
- PSMR family
- Purine/pyrimidine phosphoribosyltransferase family
- Radical SAM superfamily
- RAP family
- S-transferase-like (STL) superfamily
- SEDS proteins
- Ser/Thr protein kinase family
- Short-chain dehydrogenases/reductases (SDR) family
- Sigma-70 factor family
- Site-specific recombinase resolvase family
- Small heat shock protein (Hsp20) family
- Small multidrug resistance (SMR) (TC 2.A.7.1) family
- Sodium:galactoside symporter (TC 2.A.2) family
- Sodium:solute symporter (SSF) (TC 2.A.21) family
- SOS response-associated peptidase family
- Spore germination protein (SGP) (TC 2.A.3.9) family
- SscA family
- Sugar phosphate cyclases superfamily
- Sugar transporter (TC 2.A.1.1) family
- TCR/Tet family
- TerC family
- TetR family
- Thiolase-like superfamily
- Thioredoxin family
- 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family
- TPP enzyme family
- TRAFAC class translation factor GTPase superfamily
- TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily
- Transferase hexapeptide repeat family
- Transpeptidase family
- UPF0053 family
- UPF0702 family
- UPF0714 family
- UPF0750 membrane proteins
- Xanthine/uracil permease family
- Xre family
- Zinc-containing alcohol dehydrogenase family