Btr: Difference between revisions
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* '''Description:''' transcription | * '''Description:''' transcriptional activator ([[transcription factors of the AraC family|AraC family]]), (AraC family DNA-binding domain fused to [[FeuA]]-like substrate-binding domain), regulation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon <br/><br/> | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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=== Additional information=== | === Additional information=== | ||
=The protein= | =The protein= | ||
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** binding of a direct repeat in the ''[[feuA]]'' promoter region and transcription activation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon in the presence of bacillibactin or enterobactin {{PubMed|17725565,22210890}} | ** binding of a direct repeat in the ''[[feuA]]'' promoter region and transcription activation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon in the presence of bacillibactin or enterobactin {{PubMed|17725565,22210890}} | ||
* '''Protein family:''' | * '''Protein family:'''[[transcription factors of the AraC family|AraC family]] | ||
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
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=References= | =References= | ||
<pubmed>12884008,17725565, 22210890,12354229, 23199363</pubmed> | <pubmed>12884008,17725565, 22210890,12354229, 23199363 23504016 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:32, 7 June 2014
- Description: transcriptional activator (AraC family), (AraC family DNA-binding domain fused to FeuA-like substrate-binding domain), regulation of the feuA-feuB-feuC-ybbA operon
| Gene name | btr |
| Synonyms | ybbB, yzbC |
| Essential | no |
| Product | transcription activator (AraC family) |
| Function | regulation of iron acquisition |
| Gene expression levels in SubtiExpress: btr | |
| Metabolic function and regulation of this protein in SubtiPathways: btr | |
| MW, pI | 60 kDa, 6.433 |
| Gene length, protein length | 1587 bp, 529 aa |
| Immediate neighbours | feuA, ybbC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Categories containing this gene/protein
acquisition of iron, iron metabolism, transcription factors and their control
This gene is a member of the following regulons
The Btr regulon:
The gene
Basic information
- Locus tag: BSU01640
Phenotypes of a mutant
Database entries
- BsubCyc: BSU01640
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:AraC family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): enterobactin, bacillibactin (co-activators) PubMed
- Effectors of protein activity: enterobactin, bacillibactin (co-activators) PubMed
- Interactions:
- Btr-RNA polymerase (perhaps SigA) PubMed
Database entries
- BsubCyc: BSU01640
- Structure:
- UniProt: P40408
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: btr PubMed
- Sigma factor:
- Additional information:
- the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
<pubmed>12884008,17725565, 22210890,12354229, 23199363 23504016 </pubmed>