MenB: Difference between revisions
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<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=menB_3148901_3149716_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:menB_expression.png|500px]] | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=menB_3148901_3149716_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:menB_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30800]] | ||
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Revision as of 14:23, 16 May 2013
- Description: naphthoate synthase
| Gene name | menB |
| Synonyms | |
| Essential | yes PubMed |
| Product | naphthoate synthase |
| Function | biosynthesis of menaquinone |
| Gene expression levels in SubtiExpress: menB | |
| Metabolic function and regulation of this protein in SubtiPathways: Menaquinone | |
| MW, pI | 29 kDa, 5.343 |
| Gene length, protein length | 813 bp, 271 aa |
| Immediate neighbours | menE, ytxM |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Categories containing this gene/protein
biosynthesis of cofactors, essential genes, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30800
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: o-succinylbenzoyl-CoA = CoA + 1,4-dihydroxy-2-naphthoate (according to Swiss-Prot)
- Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- phosphorylated on Arg-78 and Arg-269 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1RJM (from Mycobacterium tuberculosis, 48% identity, 61% similarity)
- UniProt: P23966
- KEGG entry: [3]
- E.C. number: 4.1.3.36
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
<pubmed>9387221,1629163,8550504 22517742</pubmed>