FbpB

• Description: Fur-regulated basic protein, acts as RNA chaperone for fsrA, response to iron limitation
  
  

Gene name	fbpB
Synonyms	ydbN
Essential	no
Product	Fur-regulated basic protein, acts as RNA chaperone for fsrA, response to iron limitation
Function	RNA chaperone
MW, pI	6 kDa, 9.9
Gene length, protein length	177 bp, 59 aa
Immediate neighbours	ydbM, fbpA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context

Categories containing this gene/protein

acquisition of iron, iron metabolism, RNA chaperones, short peptides

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU04530

Phenotypes of a mutant

• transcription profile of a fbpA fbpB double mutant strain: GEO PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

• GEO entry: GEO PubMed

Additional information

The sequence of the former ydbN gene was corrected, and does now contain two genes, fbpA and fbpB. PubMed

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P96609

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: fbpA-fbpB PubMed

• Sigma factor:

• Regulation:
  • induced upon iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:
  • The mRNA has a long 5' leader region. This may indicate RNA-based regulation PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>12354229,18697947, 20525796 </pubmed>