SerC

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  • Description: 3-phosphoserine aminotransferase

Gene name serC
Synonyms yhaF
Essential no
Product 3-phosphoserine aminotransferase
Function biosynthesis of serine
Gene expression levels in SubtiExpress: serC
Metabolic function and regulation of this protein in SubtiPathways:
serC
MW, pI 39 kDa, 5.522
Gene length, protein length 1077 bp, 359 aa
Immediate neighbours trpP, hit
Sequences Protein DNA DNA_with_flanks
Genetic context
SerC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SerC expression.png















Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, most abundant proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU10020

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate (according to Swiss-Prot)
  • Protein family: SerC subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • belongs to the 100 most abundant proteins PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 2756 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 5019 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Christine Eymann, Annette Dreisbach, Dirk Albrecht, Jörg Bernhardt, Dörte Becher, Sandy Gentner, Le Thi Tam, Knut Büttner, Gerrit Buurman, Christian Scharf, Simone Venz, Uwe Völker, Michael Hecker
A comprehensive proteome map of growing Bacillus subtilis cells.
Proteomics: 2004, 4(10);2849-76
[PubMed:15378759] [WorldCat.org] [DOI] (P p)