PghL

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  • Description: phage-derived gamma polyglutamic acid hydrolase, sporulation protein

Gene name pghL
Synonyms yndL
Essential no
Product phage-derived gamma polyglutamic acid hydrolase
Function polyglutamic acid degradation
Gene expression levels in SubtiExpress: pghL
MW, pI 28 kDa, 6.92
Gene length, protein length 756 bp, 252 aa
Immediate neighbours surA, yndM
Sequences Protein DNA DNA_with_flanks
Genetic context
YndL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YndL expression.png















Categories containing this gene/protein

capsule biosynthesis and degradation, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigK regulon

The gene

Basic information

  • Locus tag: BSU17820

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • hyhrolysis of polyglutamic acid PubMed
  • Protein family: UPF0714 family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [4]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Stefania Mamberti, Paola Prati, Paolo Cremaschi, Claudio Seppi, Carlo F Morelli, Alessandro Galizzi, Massimo Fabbi, Cinzia Calvio
γ-PGA Hydrolases of Phage Origin in Bacillus subtilis and Other Microbial Genomes.
PLoS One: 2015, 10(7);e0130810
[PubMed:26158264] [WorldCat.org] [DOI] (I e)

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)

Jessica M Silvaggi, John B Perkins, Richard Losick
Genes for small, noncoding RNAs under sporulation control in Bacillus subtilis.
J Bacteriol: 2006, 188(2);532-41
[PubMed:16385044] [WorldCat.org] [DOI] (P p)