Mycoplasma

Reviews

Cedric Blötz, Jörg Stülke
Glycerol metabolism and its implication in virulence in Mycoplasma.
FEMS Microbiol Rev: 2017, 41(5);640-652
[PubMed:28961963] [WorldCat.org] [DOI] (I p)

Sven Halbedel, Claudine Hames, Jörg Stülke
Regulation of carbon metabolism in the mollicutes and its relation to virulence.
J Mol Microbiol Biotechnol: 2007, 12(1-2);147-54
[PubMed:17183222] [WorldCat.org] [DOI] (P p)

Global analyses

Eva Yus, Verónica Lloréns-Rico, Sira Martínez, Carolina Gallo, Hinnerk Eilers, Cedric Blötz, Jörg Stülke, Maria Lluch-Senar, Luis Serrano
Determination of the Gene Regulatory Network of a Genome-Reduced Bacterium Highlights Alternative Regulation Independent of Transcription Factors.
Cell Syst: 2019, 9(2);143-158.e13
[PubMed:31445891] [WorldCat.org] [DOI] (I p)

Maria Lluch-Senar, Javier Delgado, Wei-Hua Chen, Verónica Lloréns-Rico, Francis J O'Reilly, Judith Ah Wodke, E Besray Unal, Eva Yus, Sira Martínez, Robert J Nichols, Tony Ferrar, Ana Vivancos, Arne Schmeisky, Jörg Stülke, Vera van Noort, Anne-Claude Gavin, Peer Bork, Luis Serrano
Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium.
Mol Syst Biol: 2015, 11(1);780
[PubMed:25609650] [WorldCat.org] [DOI] (I e)

Vera van Noort, Jan Seebacher, Samuel Bader, Shabaz Mohammed, Ivana Vonkova, Matthew J Betts, Sebastian Kühner, Runjun Kumar, Tobias Maier, Martina O'Flaherty, Vladimir Rybin, Arne Schmeisky, Eva Yus, Jörg Stülke, Luis Serrano, Robert B Russell, Albert J R Heck, Peer Bork, Anne-Claude Gavin
Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
Mol Syst Biol: 2012, 8;571
[PubMed:22373819] [WorldCat.org] [DOI] (I e)

Sebastian R Schmidl, Katrin Gronau, Nico Pietack, Michael Hecker, Dörte Becher, Jörg Stülke
The phosphoproteome of the minimal bacterium Mycoplasma pneumoniae: analysis of the complete known Ser/Thr kinome suggests the existence of novel kinases.
Mol Cell Proteomics: 2010, 9(6);1228-42
[PubMed:20097688] [WorldCat.org] [DOI] (I p)

Sebastian R Schmidl, Katrin Gronau, Claudine Hames, Julia Busse, Dörte Becher, Michael Hecker, Jörg Stülke
The stability of cytadherence proteins in Mycoplasma pneumoniae requires activity of the protein kinase PrkC.
Infect Immun: 2010, 78(1);184-92
[PubMed:19858294] [WorldCat.org] [DOI] (I p)

Host-pathogen interaction

Cedric Blötz, Neil Singh, Roger Dumke, Jörg Stülke
##Title##
Front Microbiol: 2020, 11;685
[PubMed:32373096] [WorldCat.org] [DOI] (P e)

Methods

Cedric Blötz, Carole Lartigue, Yanina Valverde Timana, Estelle Ruiz, Bernhard Paetzold, Julia Busse, Jörg Stülke
Development of a replicating plasmid based on the native oriC in Mycoplasma pneumoniae.
Microbiology (Reading): 2018, 164(11);1372-1382
[PubMed:30252643] [WorldCat.org] [DOI] (I p)

Sebastian R Schmidl, Claudine Hames, Jörg Stülke
Expression of Mycoplasma proteins carrying an affinity tag in M. pneumoniae allows rapid purification and circumvents problems related to the aberrant genetic code.
Appl Environ Microbiol: 2007, 73(23);7799-801
[PubMed:17933931] [WorldCat.org] [DOI] (I p)

Sven Halbedel, Jörg Stülke
Tools for the genetic analysis of Mycoplasma.
Int J Med Microbiol: 2007, 297(1);37-44
[PubMed:17223385] [WorldCat.org] [DOI] (P p)

Sven Halbedel, Julia Busse, Sebastian R Schmidl, Jörg Stülke
Regulatory protein phosphorylation in Mycoplasma pneumoniae. A PP2C-type phosphatase serves to dephosphorylate HPr(Ser-P).
J Biol Chem: 2006, 281(36);26253-9
[PubMed:16857667] [WorldCat.org] [DOI] (P p)

Sven Halbedel, Jörg Stülke
Probing in vivo promoter activities in Mycoplasma pneumoniae: a system for generation of single-copy reporter constructs.
Appl Environ Microbiol: 2006, 72(2);1696-9
[PubMed:16461731] [WorldCat.org] [DOI] (P p)

Claudine Hames, Sven Halbedel, Oliver Schilling, Jörg Stülke
Multiple-mutation reaction: a method for simultaneous introduction of multiple mutations into the glpK gene of Mycoplasma pneumoniae.
Appl Environ Microbiol: 2005, 71(7);4097-100
[PubMed:16000825] [WorldCat.org] [DOI] (P p)

Metabolism

Cedric Blötz, Katrin Treffon, Volkhard Kaever, Frank Schwede, Elke Hammer, Jörg Stülke
##Title##
Front Microbiol: 2017, 8;1328
[PubMed:28751888] [WorldCat.org] [DOI] (P e)

Stephanie Großhennig, Till Ischebeck, Johannes Gibhardt, Julia Busse, Ivo Feussner, Jörg Stülke
Hydrogen sulfide is a novel potential virulence factor of Mycoplasma pneumoniae: characterization of the unusual cysteine desulfurase/desulfhydrase HapE.
Mol Microbiol: 2016, 100(1);42-54
[PubMed:26711628] [WorldCat.org] [DOI] (I p)

Liya Wang, Sebastian R Schmidl, Jörg Stülke
Mycoplasma pneumoniae thymidine phosphorylase.
Nucleosides Nucleotides Nucleic Acids: 2014, 33(4-6);296-304
[PubMed:24940683] [WorldCat.org] [DOI] (I p)

Stephanie Großhennig, Sebastian R Schmidl, G Schmeisky, Julia Busse, Jörg Stülke
Implication of glycerol and phospholipid transporters in Mycoplasma pneumoniae growth and virulence.
Infect Immun: 2013, 81(3);896-904
[PubMed:23297388] [WorldCat.org] [DOI] (I p)

Sebastian R Schmidl, Andreas Otto, Maria Lluch-Senar, Jaume Piñol, Julia Busse, Dörte Becher, Jörg Stülke
A trigger enzyme in Mycoplasma pneumoniae: impact of the glycerophosphodiesterase GlpQ on virulence and gene expression.
PLoS Pathog: 2011, 7(9);e1002263
[PubMed:21966272] [WorldCat.org] [DOI] (I p)

Pavel Dutow, Sebastian R Schmidl, Meike Ridderbusch, Jörg Stülke
Interactions between glycolytic enzymes of Mycoplasma pneumoniae.
J Mol Microbiol Biotechnol: 2010, 19(3);134-9
[PubMed:20924199] [WorldCat.org] [DOI] (I p)

Liya Wang, Claudine Hames, Sebastian R Schmidl, Jörg Stülke
Upregulation of thymidine kinase activity compensates for loss of thymidylate synthase activity in Mycoplasma pneumoniae.
Mol Microbiol: 2010, 77(6);1502-11
[PubMed:20860090] [WorldCat.org] [DOI] (I p)

Claudine Hames, Sven Halbedel, Michael Hoppert, Joachim Frey, Jörg Stülke
Glycerol metabolism is important for cytotoxicity of Mycoplasma pneumoniae.
J Bacteriol: 2009, 191(3);747-53
[PubMed:19028882] [WorldCat.org] [DOI] (I p)

Sven Halbedel, Hinnerk Eilers, Beate Jonas, Julia Busse, Michael Hecker, Susanne Engelmann, Jörg Stülke
Transcription in Mycoplasma pneumoniae: analysis of the promoters of the ackA and ldh genes.
J Mol Biol: 2007, 371(3);596-607
[PubMed:17586527] [WorldCat.org] [DOI] (P p)

The phosphotransferase system

Sven Halbedel, Julia Busse, Sebastian R Schmidl, Jörg Stülke
Regulatory protein phosphorylation in Mycoplasma pneumoniae. A PP2C-type phosphatase serves to dephosphorylate HPr(Ser-P).
J Biol Chem: 2006, 281(36);26253-9
[PubMed:16857667] [WorldCat.org] [DOI] (P p)

Sven Halbedel, Jörg Stülke
Dual phosphorylation of Mycoplasma pneumoniae HPr by Enzyme I and HPr kinase suggests an extended phosphoryl group susceptibility of HPr.
FEMS Microbiol Lett: 2005, 247(2);193-8
[PubMed:15927419] [WorldCat.org] [DOI] (P p)

Sven Halbedel, Claudine Hames, Jörg Stülke
In vivo activity of enzymatic and regulatory components of the phosphoenolpyruvate:sugar phosphotransferase system in Mycoplasma pneumoniae.
J Bacteriol: 2004, 186(23);7936-43
[PubMed:15547265] [WorldCat.org] [DOI] (P p)

Matthias Merzbacher, Christian Detsch, Wolfgang Hillen, Jörg Stülke
Mycoplasma pneumoniae HPr kinase/phosphorylase.
Eur J Biochem: 2004, 271(2);367-74
[PubMed:14717704] [WorldCat.org] [DOI] (P p)

Gregory S Allen, Katrin Steinhauer, Wolfgang Hillen, Jörg Stülke, Richard G Brennan
Crystal structure of HPr kinase/phosphatase from Mycoplasma pneumoniae.
J Mol Biol: 2003, 326(4);1203-17
[PubMed:12589763] [WorldCat.org] [DOI] (P p)

Katrin Steinhauer, Tanja Jepp, Wolfgang Hillen, Jörg Stülke
A novel mode of control of Mycoplasma pneumoniae HPr kinase/phosphatase activity reflects its parasitic lifestyle.
Microbiology (Reading): 2002, 148(Pt 10);3277-3284
[PubMed:12368461] [WorldCat.org] [DOI] (P p)

Katrin Steinhauer, Gregory S Allen, Wolfgang Hillen, Jörg Stülke, Richard G Brennan
Crystallization, preliminary X-ray analysis and biophysical characterization of HPr kinase/phosphatase of Mycoplasma pneumoniae.
Acta Crystallogr D Biol Crystallogr: 2002, 58(Pt 3);515-8
[PubMed:11856840] [WorldCat.org] [DOI] (P p)