Difference between revisions of "MenB"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[biosynthesis of cofactors]]}}, | {{SubtiWiki category|[[biosynthesis of cofactors]]}}, | ||
| − | {{SubtiWiki category|[[essential genes]]}} | + | {{SubtiWiki category|[[essential genes]]}}, |
| + | {{SubtiWiki category|[[phosphoproteins]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
Revision as of 15:24, 20 April 2012
- Description: naphthoate synthase
| Gene name | menB |
| Synonyms | |
| Essential | yes PubMed |
| Product | naphthoate synthase |
| Function | biosynthesis of menaquinone |
| Metabolic function and regulation of this protein in SubtiPathways: Menaquinone | |
| MW, pI | 29 kDa, 5.343 |
| Gene length, protein length | 813 bp, 271 aa |
| Immediate neighbours | menE, ytxM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, essential genes, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30800
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: o-succinylbenzoyl-CoA = CoA + 1,4-dihydroxy-2-naphthoate (according to Swiss-Prot)
- Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 1RJM (from Mycobacterium tuberculosis, 48% identity, 61% similarity)
- UniProt: P23966
- KEGG entry: [3]
- E.C. number: 4.1.3.36
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221]
[WorldCat.org]
[DOI]
(P p)
X Qin, H W Taber
Transcriptional regulation of the Bacillus subtilis menp1 promoter.
J Bacteriol: 1996, 178(3);705-13
[PubMed:8550504]
[WorldCat.org]
[DOI]
(P p)
J R Driscoll, H W Taber
Sequence organization and regulation of the Bacillus subtilis menBE operon.
J Bacteriol: 1992, 174(15);5063-71
[PubMed:1629163]
[WorldCat.org]
[DOI]
(P p)
