FlgL

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  • Description: flagellar hook-associated protein 3 (HAP3), thought to form the hook-filament junction upon which the FliD cap is assembled

Gene name flgL
Synonyms yviD
Essential no
Product flagellar hook-associated protein 3 (HAP3)
Function motility and chemotaxis
Gene expression levels in SubtiExpress: flgL
MW, pI 32 kDa, 4.42
Gene length, protein length 894 bp, 298 aa
Immediate neighbours yviE, flgK
Sequences Protein DNA DNA_with_flanks
Genetic context
FlgL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FlgL expression.png















Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

ComK regulon, DegU regulon, SigD regulon

The gene

Basic information

  • Locus tag: BSU35400

Phenotypes of a mutant

  • the mutation suppresses the mucoid phenotype of motA or motB mutants PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial flagellin family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jia Mun Chan, Sarah B Guttenplan, Daniel B Kearns
Defects in the flagellar motor increase synthesis of poly-γ-glutamate in Bacillus subtilis.
J Bacteriol: 2014, 196(4);740-53
[PubMed:24296669] [WorldCat.org] [DOI] (I p)

Yi-Huang Hsueh, Loralyn M Cozy, Lok-To Sham, Rebecca A Calvo, Alina D Gutu, Malcolm E Winkler, Daniel B Kearns
DegU-phosphate activates expression of the anti-sigma factor FlgM in Bacillus subtilis.
Mol Microbiol: 2011, 81(4);1092-108
[PubMed:21736639] [WorldCat.org] [DOI] (I p)

D B Mirel, P Lauer, M J Chamberlin
Identification of flagellar synthesis regulatory and structural genes in a sigma D-dependent operon of Bacillus subtilis.
J Bacteriol: 1994, 176(15);4492-500
[PubMed:8045879] [WorldCat.org] [DOI] (P p)

J A Londoño-Vallejo, D Dubnau
comF, a Bacillus subtilis late competence locus, encodes a protein similar to ATP-dependent RNA/DNA helicases.
Mol Microbiol: 1993, 9(1);119-31
[PubMed:8412657] [WorldCat.org] [DOI] (P p)