AraD

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  • Description: L-ribulose-phosphate 4-epimerase

Gene name araD
Synonyms
Essential no
Product L-ribulose-phosphate 4-epimerase
Function arabinose utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 25 kDa, 5.243
Gene length, protein length 687 bp, 229 aa
Immediate neighbours araL, araB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AraD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU28780

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-ribulose 5-phosphate = D-xylulose 5-phosphate (according to Swiss-Prot)
  • Protein family: AraD/fucA subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
    • repressed in the absence of arabinose (AraR) PubMed
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References