DegU
- Description: two-component response regulator, regulation of degradative enzyme and genetic competence, involved in activation of capsule biosynthetic operon expression (together with SwrAA), non-phosphorylated DegU is required for swarming motility PubMed
Gene name | degU |
Synonyms | sacU, iep |
Essential | no |
Product | two-component response regulator |
Function | regulation of degradative enzyme and genetic competence
of genetic competence |
MW, pI | 25 kDa, 5.602 |
Gene length, protein length | 687 bp, 229 aa |
Immediate neighbours | yviA, degS |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
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The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activator of degradative enzyme genes (sacB and degQ) and of comK expression
- Protein family:
- Paralogous protein(s):
Genes controlled by DegU
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P13800
- KEGG entry: BSU35490
- E.C. number:
Additional information
Expression and regulation
- Regulation: induced in the presence of ammonium (TnrA)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References