PurK

• Description: phosphoribosylaminoimidazole carboxylase (ATP-dependent)
  
  

Gene name	purK
Synonyms
Essential	no
Product	phosphoribosylaminoimidazole carboxylase (ATP-dependent)
Function	purine biosynthesis
MW, pI	42 kDa, 5.124
Gene length, protein length	1137 bp, 379 aa
Immediate neighbours	purE, purB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ATP-grasp domain (according to Swiss-Prot)

• Paralogous protein(s): PurT

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: P12045

• KEGG entry: [3]

• E.C. number: 4.1.1.21

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed