PghC

• Description: phage-derived gamma polyglutamic acid hydrolase
  
  

Gene name	ymaC
Synonyms
Essential	no
Product	phage-derived gamma polyglutamic acid hydrolase
Function	polyglutamic acid degradation
Gene expression levels in SubtiExpress: ymaC
MW, pI	26 kDa, 8.295
Gene length, protein length	705 bp, 235 aa
Immediate neighbours	ymzE/2, ymaD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

capsule biosynthesis and degradation, membrane proteins

The gene

Basic information

• Locus tag: BSU17270

Database entries

• BsubCyc: BSU17270

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • hyhrolysis of polyglutamic acid PubMed

• Protein family: UPF0714 family (according to Swiss-Prot)

• Paralogous protein(s): PghB, PghL, PghZ

Extended information on the protein

• Kinetic information:

• Domains: DUF867 [2], gamma-PGA hydrolase domain PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU17270

• Structure:

• UniProt: O31789

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ymaC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Stefania Mamberti, Paola Prati, Paolo Cremaschi, Claudio Seppi, Carlo F Morelli, Alessandro Galizzi, Massimo Fabbi, Cinzia Calvio
γ-PGA Hydrolases of Phage Origin in Bacillus subtilis and Other Microbial Genomes.
PLoS One: 2015, 10(7);e0130810
[PubMed:26158264] [WorldCat.org] [DOI] (I e)