SpoVM

• Description: required for normal spore cortex and coat synthesis, inhibits the proteolytic activity of FtsH (adaptor protein)
  
  

Gene name	spoVM
Synonyms
Essential	no
Product	spore coat morphogenetic protein
Function	spore cortex and coat synthesis
Gene expression levels in SubtiExpress: spoVM
Interactions involving this protein in SubtInteract: SpoVM
MW, pI	2 kDa, 11.026
Gene length, protein length	78 bp, 26 aa
Immediate neighbours	yloS, rpmB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU15810

Phenotypes of a mutant

• reduction of sporulation efficiency due to defects in spore coat and cortex assembly PubMed

Database entries

• BsubCyc: BSU15810

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • anchors the basement layer of the spore coat to the surface of the developing spore PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: contains an amphipathic alpha-helix

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • SpoIVA-SpoVM-SpoVID PubMed
  • SpoVM-FtsH PubMed

• Localization:
  • around the surface of the developing forespore PubMed
  • spore membrane, recognizes membrane curvature PubMed
  • spore coat (basement), localization depends on SpoIVA PubMed

Database entries

• BsubCyc: BSU15810

• Structure:

• UniProt: P37817

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVM PubMed

• Expression browser: spoVM PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed in mother cell during sporulation (SigE, SpoIIID) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: