SufS

• Description: cysteine desulfurase, cysteine:SufU sulfuryl transferase
  
  

Gene name	sufS
Synonyms	yurW, csd
Essential	yes PubMed
Product	cysteine desulfurase
Function	formation of iron-sulfur clusters in proteins
Gene expression levels in SubtiExpress: sufS
Interactions involving this protein in SubtInteract: SufS
Metabolic function and regulation of this protein in SubtiPathways: SufS
MW, pI	44 kDa, 5.199
Gene length, protein length	1218 bp, 406 aa
Immediate neighbours	sufU, sufD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

iron metabolism, essential genes

The gene

Basic information

• Locus tag: BSU32690

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU32690

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transfer of iron to SufU PubMed

• Protein family: Csd subfamily (according to Swiss-Prot)

• Paralogous protein(s): NifS, YrvO, NifZ, YcbU

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity: interaction with SufU enhances the activity of SufS 40-fold PubMed

• Interactions: SufS-SufU PubMed

• Localization:

Database entries

• BsubCyc: BSU32690

• Structure:

• UniProt: O32164

• KEGG entry: [2]

• E.C. number: 2.8.1.7

Expression and regulation

• Operon: sufC-sufD-sufS-sufU-sufB PubMed

• Expression browser: sufS PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 1121 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1680 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 3779 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 2246 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 2854 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: