DhaS

• Description: 3-hydroxypropionaldehyde-specific aldehyde dehydrogenase (NAD)
  
  

Gene name	dhaS
Synonyms
Essential	no
Product	aldehyde dehydrogenase (NAD)
Function	unknown
Gene expression levels in SubtiExpress: dhaS
MW, pI	53 kDa, 5.021
Gene length, protein length	1485 bp, 495 aa
Immediate neighbours	yozC, sqhC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

poorly characterized/ putative enzymes

The gene

Basic information

• Locus tag: BSU19310

Database entries

• BsubCyc: BSU19310

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): YfmT, AldY, YcbD, GabD, GbsA, IolA, PutC, RocA, AldX, YwdH

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU19310

• Structure: 3RHH (from from Bacillus halodurans C-125 complexed with NADP, 32% identity, 64% similarity)

• UniProt: O34660

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: dhaS PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 780 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 2339 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 1628 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 1464 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 6161 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Mingyue Su, Ying Li, Xizhen Ge, Pingfang Tian
3-Hydroxypropionaldehyde-specific aldehyde dehydrogenase from Bacillus subtilis catalyzes 3-hydroxypropionic acid production in Klebsiella pneumoniae.
Biotechnol Lett: 2015, 37(3);717-24
[PubMed:25409630] [WorldCat.org] [DOI] (I p)