YukE

• Description: secreted protein of the WXG100 superfamily, homolog of virulence factor EsxA
  
  

Gene name	yukE
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yukE
MW, pI	8 kDa, 7.909
Gene length, protein length	240 bp, 80 aa
Immediate neighbours	yukD, adeR
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

proteins of unknown function, most abundant proteins

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

• Locus tag: BSU31910

Database entries

• BsubCyc: BSU31910

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: WXG100 superfamily (pfam06013) PubMed

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • forms dimers PubMed

• Localization:
  • secreted, by the type VII protein secretion system YukD-YukC-YukB-YueB-YueC PubMed

Database entries

• BsubCyc: BSU31910

• Structure:

• UniProt: C0SP85

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yukE-yukD-yukC-yukB-yueB-yueC PubMed

• Expression browser: yukE PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • not expressed in the lab strain 168, due to lack of DegU-P PubMed
  • expressed in the stationary phase PubMed

• Regulatory mechanism:
  • DegU-P: transcription activation PubMed

• Additional information:
  • belongs to the 100 most abundant proteins PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 1775 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 23591 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 10799 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 11580 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 4748 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: