YetO

• Description: cytochrome P450 (CYP102A2)/ NADPH-cytochrome P450 reductase
  
  

Gene name	yetO
Synonyms	yfnJ , cypD
Essential	no
Product	NADPH-cytochrome P450 reductase
Function	fatty acid metabolism
Gene expression levels in SubtiExpress: yetO
Metabolic function and regulation of this protein in SubtiPathways: YetO
MW, pI	119 kDa, 5.732
Gene length, protein length	3183 bp, 1061 aa
Immediate neighbours	yetN, yfnI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

electron transport/ other, lipid metabolism/ other

The gene

Basic information

• Locus tag: BSU07250

Database entries

• BsubCyc: BSU07250

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • oxidation of even- and odd-chain saturated and unsaturated fatty acids to the respective omega-3, omega-2 and omega-1 hydroxylated fatty acids PubMed

• Protein family:

• Paralogous protein(s): YrhJ

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU07250

• Structure: 2X7Y (from Bacillus megaterium; 66% identity, 87% similarity)

• UniProt: O08394

• KEGG entry: [2]

• E.C. number: 1.6.2.4

Expression and regulation

• Operon:

• Expression browser: yetO PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 287 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1372 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: