Cytochrome P450 family
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Contents
- 1 The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals
- 2 B. subtilis encodes eight cytochromes P450:
- 3 P450 in Bacillus
- 4 Relevant reviews
The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals
B. subtilis encodes eight cytochromes P450:
- BioI (CYP107H1)
- CypA (CYP107J1)
- CypC (CYP152A1)
- CypX (CYP134A1)
- PksS (CYP107K1)
- YetO (CYP102A2)
- YjiB (CYP109B1)
- YrhJ (CYP102A3)
P450 in Bacillus
Yiru Wang, Ying Li
The CYP134 family in Gram-positive bacteria: From Bacillus to beyond, an orphan P450 lineage awaiting functional discovery.
Biochimie: 2025, 242;9-21
[PubMed:41349902]
[WorldCat.org]
[DOI]
(I a)
Mattias C U Gustafsson, Olivier Roitel, Ker R Marshall, Michael A Noble, Stephen K Chapman, Antonio Pessegueiro, Armand J Fulco, Myles R Cheesman, Claes von Wachenfeldt, Andrew W Munro
Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
Biochemistry: 2004, 43(18);5474-87
[PubMed:15122913]
[WorldCat.org]
[DOI]
(P p)
Relevant reviews
