Cytochrome P450 family

B. subtilis encodes eight cytochromes P450:

• BioI (CYP107H1)
• CypA (CYP107J1)
• CypC (CYP152A1)
• CypX (CYP134A1)
• PksS (CYP107K1)
• YetO (CYP102A2)
• YjiB (CYP109B1)
• YrhJ (CYP102A3)

P450 in Bacillus

Mattias C U Gustafsson, Olivier Roitel, Ker R Marshall, Michael A Noble, Stephen K Chapman, Antonio Pessegueiro, Armand J Fulco, Myles R Cheesman, Claes von Wachenfeldt, Andrew W Munro
Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
Biochemistry: 2004, 43(18);5474-87
[PubMed:15122913] [WorldCat.org] [DOI] (P p)

Relevant reviews

Courtney M Krest, Elizabeth L Onderko, Timothy H Yosca, Julio C Calixto, Richard F Karp, Jovan Livada, Jonathan Rittle, Michael T Green
Reactive intermediates in cytochrome p450 catalysis.
J Biol Chem: 2013, 288(24);17074-81
[PubMed:23632017] [WorldCat.org] [DOI] (I p)

F Peter Guengerich, Andrew W Munro
Unusual cytochrome p450 enzymes and reactions.
J Biol Chem: 2013, 288(24);17065-73
[PubMed:23632016] [WorldCat.org] [DOI] (I p)

F Peter Guengerich
New trends in cytochrome p450 research at the half-century mark.
J Biol Chem: 2013, 288(24);17063-4
[PubMed:23632015] [WorldCat.org] [DOI] (I p)

Peter Hlavica, Michael Lehnerer
Oxidative biotransformation of fatty acids by cytochromes P450: predicted key structural elements orchestrating substrate specificity, regioselectivity and catalytic efficiency.
Curr Drug Metab: 2010, 11(1);85-104
[PubMed:20302567] [WorldCat.org] [DOI] (I p)

Toshiki Furuya, Kuniki Kino
Genome mining approach for the discovery of novel cytochrome P450 biocatalysts.
Appl Microbiol Biotechnol: 2010, 86(4);991-1002
[PubMed:20177889] [WorldCat.org] [DOI] (I p)

D E Torres Pazmiño, M Winkler, A Glieder, M W Fraaije
Monooxygenases as biocatalysts: Classification, mechanistic aspects and biotechnological applications.
J Biotechnol: 2010, 146(1-2);9-24
[PubMed:20132846] [WorldCat.org] [DOI] (I p)

Tsuneo Omura
Structural diversity of cytochrome P450 enzyme system.
J Biochem: 2010, 147(3);297-306
[PubMed:20068028] [WorldCat.org] [DOI] (I p)

Santosh Kumar
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation.
Expert Opin Drug Metab Toxicol: 2010, 6(2);115-31
[PubMed:20064075] [WorldCat.org] [DOI] (I p)

Toshiki Furuya, Daisuke Shibata, Kuniki Kino
Phylogenetic analysis of Bacillus P450 monooxygenases and evaluation of their activity towards steroids.
Steroids: 2009, 74(12);906-12
[PubMed:19559718] [WorldCat.org] [DOI] (I p)

Andrew W Munro, Hazel M Girvan, Kirsty J McLean
Cytochrome P450--redox partner fusion enzymes.
Biochim Biophys Acta: 2007, 1770(3);345-59
[PubMed:17023115] [WorldCat.org] [DOI] (P p)

Minor J Coon
Cytochrome P450: nature's most versatile biological catalyst.
Annu Rev Pharmacol Toxicol: 2005, 45;1-25
[PubMed:15832443] [WorldCat.org] [DOI] (P p)

D R Nelson
Cytochrome P450 and the individuality of species.
Arch Biochem Biophys: 1999, 369(1);1-10
[PubMed:10462435] [WorldCat.org] [DOI] (P p)

K Oguri, H Yamada, H Yoshimura
Regiochemistry of cytochrome P450 isozymes.
Annu Rev Pharmacol Toxicol: 1994, 34;251-79
[PubMed:8042852] [WorldCat.org] [DOI] (P p)

A J Fulco
P450BM-3 and other inducible bacterial P450 cytochromes: biochemistry and regulation.
Annu Rev Pharmacol Toxicol: 1991, 31;177-203
[PubMed:2064373] [WorldCat.org] [DOI] (P p)