PhrI

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Gene name phrI
Synonyms
Essential no
Product phosphatase (RapI) regulator
Function control of the transfer of the
mobile genetic element ICEBs1
Gene expression levels in SubtiExpress: phrI
Interactions involving this protein in SubtInteract: PhrI
MW, pI 4 kDa, 8.907
Gene length, protein length 117 bp, 39 aa
Immediate neighbours rapI, yddM
Sequences Protein DNA DNA_with_flanks
Genetic context
PhrI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhrI expression.png















Categories containing this gene/protein

protein modification, transcription factors and their control, quorum sensing, mobile genetic elements, short peptides

This gene is a member of the following regulons

SigH regulon

The gene

Basic information

  • Locus tag: BSU05020

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds RapI and inhibits its activity, this results in contiuned repression of the genes for the transfer of the mobile genetic element ICEBs1 by ImmR PubMed
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jennifer M Auchtung, Catherine A Lee, Katherine L Garrison, Alan D Grossman
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 64(6);1515-28
[PubMed:17511812] [WorldCat.org] [DOI] (P p)

R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295] [WorldCat.org] [DOI] (P p)