ComFA
- Description: membrane-associated ATPase, may provide energy for DNA transport
| Gene name | comFA |
| Synonyms | |
| Essential | no |
| Product | ATP-binding protein |
| Function | genetic competence |
| Gene expression levels in SubtiExpress: comFA | |
| Interactions involving this protein in SubtInteract: ComFA | |
| Metabolic function and regulation of this protein in SubtiPathways: Protein secretion | |
| MW, pI | 52 kDa, 9.824 |
| Gene length, protein length | 1389 bp, 463 aa |
| Immediate neighbours | comFB, yviA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
genetic competence, membrane proteins, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35470
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: helicase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- phosphorylated on Arg-20, Arg-186, and Arg-446 PubMed
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P39145
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159]
[WorldCat.org]
[DOI]
(P p)
Original publications
Additional publications: PubMed
