MalR

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  • Description: two-component response regulator, regulation of malate uptake

Gene name malR
Synonyms yufM
Essential no
Product two-component response regulator
Function regulation of malate uptake
Gene expression levels in SubtiExpress: malR
Interactions involving this protein in SubtInteract: MalR
Metabolic function and regulation of this protein in SubtiPathways:
malR
MW, pI 26 kDa, 5.976
Gene length, protein length 705 bp, 235 aa
Immediate neighbours malK, nupN
Sequences Protein DNA DNA_with_flanks
Genetic context
YufM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MalR expression.png




























Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control, phosphoproteins

This gene is a member of the following regulons

The MalR regulon:

The gene

Basic information

  • Locus tag: BSU31530

Phenotypes of a mutant

unable to use malate as the single carbon source PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated by MalK on an Asp residue
  • Cofactor(s):
  • Effectors of protein activity: phosphorylation likely affects DNA-binding activity

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP1301 (cat), available in Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France

Your additional remarks

References