YtxM

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  • Description: similar to prolyl aminopeptidase

Gene name ytxM
Synonyms ytfB
Essential no
Product unknown
Function ubiquinone and menaquinone biosynthesis
Gene expression levels in SubtiExpress: ytxM
Metabolic function and regulation of this protein in SubtiPathways:
ytxM
MW, pI 30 kDa, 7.175
Gene length, protein length 822 bp, 274 aa
Immediate neighbours menB, menD
Sequences Protein DNA DNA_with_flanks
Genetic context
YtxM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtxM expression.png




























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU30810

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: lipase/esterase LIP3/bchO family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

M M Mehanni, A P Turnbull, S E Sedelnikova, P J Baker, S Foster, D W Rice
Crystallization and preliminary X-ray analysis of the ytxM gene product from Bacillus subtilis.
Acta Crystallogr D Biol Crystallogr: 2002, 58(Pt 12);2138-40
[PubMed:12454479] [WorldCat.org] [DOI] (P p)

H Antelmann, C Scharf, M Hecker
Phosphate starvation-inducible proteins of Bacillus subtilis: proteomics and transcriptional analysis.
J Bacteriol: 2000, 182(16);4478-90
[PubMed:10913081] [WorldCat.org] [DOI] (P p)

Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221] [WorldCat.org] [DOI] (P p)

X Qin, H W Taber
Transcriptional regulation of the Bacillus subtilis menp1 promoter.
J Bacteriol: 1996, 178(3);705-13
[PubMed:8550504] [WorldCat.org] [DOI] (P p)

J R Driscoll, H W Taber
Sequence organization and regulation of the Bacillus subtilis menBE operon.
J Bacteriol: 1992, 174(15);5063-71
[PubMed:1629163] [WorldCat.org] [DOI] (P p)