EtfA

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  • Description: electron transfer flavoprotein (alpha subunit)

Gene name etfA
Synonyms
Essential no
Product electron transfer flavoprotein (alpha subunit)
Function fatty acid degradation, calcium carbonate biomineralization
Gene expression levels in SubtiExpress: etfA
Metabolic function and regulation of this protein in SubtiPathways:
etfA
MW, pI 34 kDa, 4.652
Gene length, protein length 975 bp, 325 aa
Immediate neighbours abf2, etfB
Sequences Protein DNA DNA_with_flanks
Genetic context
EtfA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
EtfA expression.png




























Categories containing this gene/protein

electron transport/ other, utilization of lipids

This gene is a member of the following regulons

CcpA regulon, FadR regulon

The gene

Basic information

  • Locus tag: BSU28520

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ETF alpha-subunit/fixB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287] [WorldCat.org] [DOI] (P p)

Original Publications

Shigeo Tojo, Takenori Satomura, Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Catabolite repression of the Bacillus subtilis FadR regulon, which is involved in fatty acid catabolism.
J Bacteriol: 2011, 193(10);2388-95
[PubMed:21398533] [WorldCat.org] [DOI] (I p)

Massimiliano Marvasi, Pieter T Visscher, Brunella Perito, Giorgio Mastromei, Lilliam Casillas-Martínez
Physiological requirements for carbonate precipitation during biofilm development of Bacillus subtilis etfA mutant.
FEMS Microbiol Ecol: 2010, 71(3);341-50
[PubMed:20059546] [WorldCat.org] [DOI] (I p)

Hiroshi Matsuoka, Kazutake Hirooka, Yasutaro Fujita
Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation.
J Biol Chem: 2007, 282(8);5180-94
[PubMed:17189250] [WorldCat.org] [DOI] (P p)

Chiara Barabesi, Alessandro Galizzi, Giorgio Mastromei, Mila Rossi, Elena Tamburini, Brunella Perito
Bacillus subtilis gene cluster involved in calcium carbonate biomineralization.
J Bacteriol: 2007, 189(1);228-35
[PubMed:17085570] [WorldCat.org] [DOI] (P p)